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Gene Information
Gene symbol: ACHE
Gene name: acetylcholinesterase
HGNC ID: 108
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | APP | 1 hits |
| 2 | CD86 | 1 hits |
| 3 | GPI | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 11527149 | In this study, biotinylated human erythrocyte (E(hu)) decay accelerating factor, E(hu) acetylcholinesterase, and GPI-reanchored murine B7-1 and B7-2 were used as GPI-anchored reporters to characterize their plasma membrane organization and cell signalling properties following addition to Hela or Chinese hamster ovary cells. |
| 2 | 16690718 | Interestingly, a cholinesterase inhibitor currently in clinical trials, phenserine, has been shown to inhibit production of both amyloid precursor protein (APP) and A beta. |
| 3 | 16690718 | The focus of this study was to screen 144 analogs of phenserine to identify additional small molecules that inhibit APP protein synthesis, and thereby A beta production, without possessing potent acetylcholinesterase (AChE) inhibitory activity. |