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Gene Information
Gene symbol: ACOT7
Gene name: acyl-CoA thioesterase 7
HGNC ID: 24157
Synonyms: BACH, ACH1, ACT, CTE-II, LACH1, MGC1126, hBACH
Related Genes
Related Sentences
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PMID |
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1 |
22918926
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Phase I/II trials of vaccination with allogeneic dendritic cell/tumour fusions in patients with mRCC have demonstrated immunological and clinical responses in some patients, and T-cell modulating agents (e.g. antibodies against programmed death 1 and cytotoxic T lymphocyte-associated antigen-4, or soluble lymphocyte activation gene-3) and dendritic cell-activating toll-like receptor agonists have also shown encouraging evidence of efficacy in early-phase clinical trials.
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2 |
22918926
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As such, a number of other strategies are currently under investigation, including adoptive cell transfer (ACT) with T cells modified to target proteins expressed by renal tumours such as MAGE-A3/12, DR4 and TRAIL, and ACT with autologous natural killer cells.
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