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Gene Information
Gene symbol: ADAM1
Gene name: ADAM metallopeptidase domain 1 (fertilin alpha) pseudogene
HGNC ID: 187
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ADAM11 | 1 hits |
| 2 | ADAM2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 9358007 | Fertilin alpha and beta are members of the MDC (metalloproteinase-like, disintegrin-like, cysteine-rich) protein family and are expressed on the sperm surface where they have been proposed to play a role in mammalian fertilization. |
| 2 | 11750738 | These molecules include members of the ADAM (a disintegrin and a metalloprotease domain) family, i.e., testicular proteins fertilin alpha, fertilin beta, and cyritestin, which are thought to interact with integrins in the egg plasma membrane through their disintegrin domains, and a member of the cysteine-rich secretory proteins (CRISP) family, i.e., epididymal protein DE, which participates in an event subsequent to sperm-egg binding and leading to fusion through specific complementary sites localized on the fusogenic area of the egg surface. |