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Gene Information
Gene symbol: ADAM17
Gene name: ADAM metallopeptidase domain 17
HGNC ID: 195
Synonyms: cSVP, CD156B
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD40 | 1 hits |
| 2 | EGFR | 1 hits |
| 3 | FASLG | 1 hits |
| 4 | HLA-A | 1 hits |
| 5 | TRAF3 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21175594 | ADAM metallopeptidase domain 17 (ADAM17) is naturally processed through major histocompatibility complex (MHC) class I molecules and is a potential immunotherapeutic target in breast, ovarian and prostate cancers. |
| 2 | 21175594 | ADAM17 is one of the several metalloproteinases that play a key role in epidermal growth factor receptor (EGFR) signalling and has recently emerged as a new therapeutic target in several tumour types. |
| 3 | 21175594 | ADAM metallopeptidase domain 17 (ADAM17) is naturally processed through major histocompatibility complex (MHC) class I molecules and is a potential immunotherapeutic target in breast, ovarian and prostate cancers. |
| 4 | 21175594 | ADAM17 is one of the several metalloproteinases that play a key role in epidermal growth factor receptor (EGFR) signalling and has recently emerged as a new therapeutic target in several tumour types. |
| 5 | 23376446 | Expression levels of INF-γ and IL-4, which are characteristic cytokines secreted during Th1-like and Th2-like immune responses, respectively, were unchanged in vaccinated animals as compared to control animals. |
| 6 | 23376446 | Expression levels of TNF-α and some related molecules, such as ADAM17, FasL, CD40 and TRAF3 were also elevated. |