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Gene Information
Gene symbol: ADAM7
Gene name: ADAM metallopeptidase domain 7
HGNC ID: 214
Synonyms: GP-83, EAPI
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD4 | 1 hits |
| 2 | CD8A | 1 hits |
| 3 | LAMC1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 17299708 | Vaccination with VRP-GP83 induced antibodies and CD4(+) and CD8(+) T cell responses in GPCMV-seronegative female guinea pigs. |
| 2 | 23133440 | Infective trypomastigotes up-regulate the expression of laminin γ-1 (LAMC1) and thrombospondin (THBS1) to facilitate the recruitment of trypomastigotes to enhance cellular infection. |
| 3 | 23133440 | Silencing the expression of LAMC1 and THBS1 by stable RNAi dramatically reduces trypanosome infection. |
| 4 | 23133440 | T. cruzi gp83, a ligand that mediates the attachment of trypanosomes to cells to initiate infection, up-regulates LAMC1 expression to enhance cellular infection. |
| 5 | 23133440 | Infective trypomastigotes use Tc85 to interact with laminin, p45 mucin to interact with LAMC1 through galectin-3 (LGALS3), a human lectin, and calreticulin (TcCRT) to interact with TSB1 to enhance cellular infection. |
| 6 | 24856783 | Several potential immunodominant GP83-specific peptides were identified, including one epitope, LGIVHFFDN, that was noted in all guinea pigs that had a detectable CD8+ response to GP83. |