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Gene Information
Gene symbol: AGTRL1
Gene name: angiotensin II receptor-like 1
HGNC ID: 339
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | FPR2 | 1 hits |
| 2 | GPR15 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21835785 | The great majority of human immunodeficiency virus type 1 (HIV-1) strains enter CD4+ target cells by interacting with one of two coreceptors, CCR5 or CXCR4. |
| 2 | 21835785 | Here we describe a transmitted/founder (T/F) virus (ZP6248) that was profoundly impaired in its ability to utilize CCR5 and CXCR4 coreceptors on multiple CD4+ cell lines as well as primary human CD4+ T cells and macrophages in vitro yet replicated to very high titers (>80 million RNA copies/ml) in an acutely infected individual. |
| 3 | 21835785 | The ZP6248 T/F virus could also infect cell lines overexpressing the alternative coreceptors GPR15, APJ, and FPRL-1. |
| 4 | 21835785 | These results suggest that the ZP6248 T/F virus established an acute in vivo infection by using coreceptor(s) other than CCR5 or CXCR4 or that the CCR5 coreceptor existed in an unusual conformation in this individual. |