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Gene Information
Gene symbol: ATF4
Gene name: activating transcription factor 4 (tax-responsive enhancer element B67)
HGNC ID: 786
Synonyms: TAXREB67, CREB-2
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ATF6 | 1 hits |
| 2 | CASP3 | 1 hits |
| 3 | CYCS | 1 hits |
| 4 | DDIT3 | 1 hits |
| 5 | EIF2AK3 | 1 hits |
| 6 | EIF2S1 | 1 hits |
| 7 | HSPA5 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 25633898 | Finally, we discovered the over-expression of GRP78, ATF4, ATF6, PERK, eIF2α, CHOP, and cytochrome c (Cyt-c) but not IRE1, xbp-1, and caspase-3 in B.suis.S2 (HK)-attacked and B.suis.S2-infected cells, suggesting that the molecular mechanism of ER stress sensor activation by B.suis.S2 is basically concomitant with that by B.suis.S2 (HK) and that ER stress, especially the PERK pathway, plays an important role in the process of B.suis.S2 infecting EEC, which may, in part, explain the role of the uterus in the pathogenesis of B.suis.S2. |