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Gene Information
Gene symbol: ATXN1
Gene name: ataxin 1
HGNC ID: 10548
Synonyms: D6S504E, ATX1
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
24794706
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Loss of Lkb1 and Pten leads to lung squamous cell carcinoma with elevated PD-L1 expression.
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2 |
24794706
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We demonstrate that biallelic inactivation of Lkb1 and Pten in the mouse lung leads to SCC that recapitulates the histology, gene expression, and microenvironment found in human disease.
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3 |
24794706
|
Lkb1;Pten null (LP) tumors expressed the squamous markers KRT5, p63 and SOX2, and transcriptionally resembled the basal subtype of human SCC.
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4 |
24794706
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SCA1(+)NGFR(+) fractions were enriched for tumor-propagating cells (TPCs) that could serially transplant the disease in orthotopic assays.
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