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Gene Information

Gene symbol: BIK

Gene name: BCL2-interacting killer (apoptosis-inducing)

HGNC ID: 1051

Synonyms: NBK

Related Genes

#	Gene Symbol	Number of hits
1	BCL2L11	1 hits
2	BCR	1 hits
3	PMAIP1	1 hits

Related Sentences

#	PMID	Sentence
1	26184912	We demonstrate the upregulation of Bim, Bik, and Noxa during BCR signaling in vitro and that intrinsic apoptosis has a prominent role in anti-BCR antibody therapy in vivo.
2	26184912	Furthermore, lymphomas deficient in these individual BH3-only proteins display significant protection from BCR-induced cell death, whereas combined loss of Noxa and Bim offers enhanced protection in comparison with loss of Bim alone.
3	26184912	These observations indicate that BCR signaling elicits maximal cell death through upregulation of multiple BH3-only proteins; namely Bim, Bik, and Noxa.
4	26184912	We demonstrate the upregulation of Bim, Bik, and Noxa during BCR signaling in vitro and that intrinsic apoptosis has a prominent role in anti-BCR antibody therapy in vivo.
5	26184912	Furthermore, lymphomas deficient in these individual BH3-only proteins display significant protection from BCR-induced cell death, whereas combined loss of Noxa and Bim offers enhanced protection in comparison with loss of Bim alone.
6	26184912	These observations indicate that BCR signaling elicits maximal cell death through upregulation of multiple BH3-only proteins; namely Bim, Bik, and Noxa.