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Gene Information
Gene symbol: BPI
Gene name: bactericidal/permeability-increasing protein
HGNC ID: 1095
Synonyms: BPIFD1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | GUSB | 1 hits |
| 2 | IFNG | 1 hits |
| 3 | IL8 | 1 hits |
| 4 | LBP | 1 hits |
| 5 | RAB33A | 1 hits |
| 6 | SEC14L1 | 1 hits |
| 7 | TF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16714555 | Furthermore, F. tularensis LPS did not compete with a radiolabeled lipooligosaccharide from Neisseria meningitidis for binding to LBP or to the closely related PMN granule protein, bactericidal/permeability-increasing protein. |
| 2 | 18226548 | Expression of antibacterial genes, bactericidal/permeability-increasing protein/lipopolysaccharide-binding protein (BPI/LBP), g-type lysozyme and transferrin was significantly upregulated in the vaccinated fish, with maximum expression within 7 dpv. |
| 3 | 18226548 | Cytotoxic-related and cell-mediated immunity genes such as, apolipoprotein A-I and the non-specific cytotoxic cell receptor protein (NCCRP-1) had maximum expression at 3 and 7 dpv, respectively. |
| 4 | 18226548 | Significant upregulation in expression of pro-inflammatory cytokines, IL-1 beta and IL-8 was also observed in the vaccinated fish at 1 dpv. |
| 5 | 23089523 | In vaccinated fish, the gene expression of interleukin (IL) 1b, IL-10, IL-12p40 and hepcidin were significant up-regulated. |
| 6 | 23089523 | While, no measureable activations of interferon gamma (IFNγ), IL-8, cathelicidin, LBP/BPI and G-type lysozyme were found. |
| 7 | 23676757 | The study shows that transcription of SEC14L1, GUSB, BPI, CCR7 and TGFβ-1 (all P ≤ 0.05) was downregulated in TB disease compared with uninfected controls, while transcription of RAB33A was downregulated in TB disease compared with both latent TB (P < 0.05) and controls (P < 0.01). |
| 8 | 23676757 | The transcription of CD4, TGFβ-1 (P < 0.01) and the expression of IL-2 (P < 0.01) and IL-13 (P < 0.05) was upregulated in latent TB compared with that in controls. |
| 9 | 23676757 | Using the Least Absolute Shrinkage and Selection Operator (lasso) model, RAB33A alone discriminated between TB disease and latent TB (area under the curve (AUC) 77.5%), whereas a combination of RAB33A, CXCL10, SEC14L1, FOXP3 and TNFRSF1A was effective in discriminating between TB disease and controls (AUC 91.7%). |
| 10 | 23676757 | In conclusion, RAB33A is a potential biomarker for TB disease, whereas CD4, TGFβ-1 and IL-2, IL-13 may identify latent TB in children. |