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Gene Information
Gene symbol: C3
Gene name: complement component 3
HGNC ID: 1318
Synonyms: CPAMD1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCL2 | 1 hits |
| 2 | CCL5 | 1 hits |
| 3 | CD8A | 1 hits |
| 4 | F5 | 1 hits |
| 5 | HLA-A | 1 hits |
| 6 | IFNG | 1 hits |
| 7 | IL1B | 1 hits |
| 8 | IL4 | 1 hits |
| 9 | MS4A1 | 1 hits |
| 10 | MUT | 1 hits |
| 11 | STAT1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 2895317 | Additionally, complement component C3 deficient serum lacks the labile activity although Clq deficient serum contains the labile factor. |
| 2 | 12517942 | Complement component 3 is required for optimal expansion of CD8 T cells during a systemic viral infection. |
| 3 | 12517942 | Studies in complement receptor 1/2 (CR1/CR2)-deficient mice showed that regulation of LCMV-specific CD8 T cell responses by C3 is not dependent upon CR1/CR2. |
| 4 | 15728729 | A second chimeric virus based on clade D HIV-1/NDK was also highly infectious in mice; it was detected in both spleen and brain 3 wk after tail vein inoculation, and it induced expression of infection response genes, MCP-1, STAT1, IL-1beta, and complement component C3, in brain tissue as determined by quantitative real-time PCR. |
| 5 | 16185791 | Using microarray analysis, humoral defense-related genes such as complement component C3, complement regulatory plasma proteins, IgM, IgD, MHC class II-associated invariant chain and CD20 receptor were observed to be up-regulated by the VHSg recombinant protein vaccine at 1 or 21 days post vaccination. |
| 6 | 19095381 | Statistical analysis of qRT-PCR data revealed that four genes, complement component C3, IFN-gamma, IL-4 and RANTES were downregulated in infected animals (P<0.05). |
| 7 | 19095381 | The mRNA levels of IFN-gamma and C3 showed a peak (>15-fold increase) at 5 wpi, whereas transcripts for RANTES and IL-4 showed a peak (>2-fold increase) at 13 wpi in BCG-immunized animals when compared to non-immunized controls. |
| 8 | 22848869 | The study of host-pathogen interactions identified biomarkers of resistance/susceptibility to tuberculosis in wild boar such as complement component 3 (C3) and methylmalonyl coenzyme A mutase (MUT) that were used for vaccine development. |