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Gene Information
Gene symbol: CASP12
Gene name: caspase 12 (gene/pseudogene)
HGNC ID: 19004
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | BCL2L10 | 1 hits |
| 2 | CD8A | 1 hits |
| 3 | NOL3 | 1 hits |
| 4 | PAK7 | 1 hits |
| 5 | TNFRSF11B | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21325489 | This treatment with shRNA Casp12, administered twice within the first 10 days following vaccine administration, increased antigen expression 7-fold, the antigen-specific CD8(+) T cell immune response 6-fold, and antigen-specific antibody production 5-fold. |
| 2 | 25195511 | Transgenic 4-1BBL-engineered vaccine stimulates potent Gag-specific therapeutic and long-term immunity via increased priming of CD44(+)CD62L(high) IL-7R(+) CTLs with up- and downregulation of anti- and pro-apoptosis genes. |
| 3 | 25195511 | OVA-Texo/4-1BBL-stimulated CTLs, which have a CD44(+)CD62L(high) IL-7R(+) phenotype, are likely memory CTL precursors, demonstrating prolonged survival and enhanced differentiation into memory CTLs with functional recall responses and long-term immunity against BL6-10OVA melanoma. |
| 4 | 25195511 | In addition, we demonstrate that OVA-Texo/4-1BBL-stimulated CTLs up- and downregulate the expression of anti-apoptosis (Bcl2l10, Naip1, Nol3, Pak7 and Tnfrsf11b) and pro-apoptosis (Casp12, Trp63 and Trp73) genes, respectively, by RT(2) Profiler PCR array analysis. |