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Gene Information
Gene symbol: CCKBR
Gene name: cholecystokinin B receptor
HGNC ID: 1571
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCK | 1 hits |
| 2 | CYCS | 1 hits |
| 3 | GAST | 1 hits |
| 4 | GRP | 1 hits |
| 5 | GRPR | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 1708369 | Immunization experiments in guinea pigs with the synthetic hybrids led to surprisingly strong immune responses with anti-little-gastrin antibody titers comparable to those induced by the iso-1-cytochrome c/little-gastrin-[2-17] conjugate as carrier-hapten system. |
| 2 | 1708369 | Additionally, the gastrin receptor-like specificity of the antibodies indicates that both the synthetic hybrids and the cytochrome c conjugate allow for expression of a little-gastrin-specific conformational epitope similar to the bioactive structure of this hormone. |
| 3 | 11156225 | The antibodies were of an affinity high enough to compete with the cholecystokinin B/gastrin receptor for G17 binding with adequate capacity to neutralize postprandial gastrin surges. |
| 4 | 11212260 | Some colorectal adenomas express cholecystokinin B/gastrin receptor mRNA, and thus hypergastrinemia may increase progression through the adenoma-carcinoma sequence. |
| 5 | 11212260 | Serum gastrin levels in APC(Min-/+) mice were elevated 5-6-fold by oral administration of omeprazole (75 mg/kg). |
| 6 | 16699262 | Some of them (namely potassium-competitive acid blockers (P-CABs) and CCK2-receptor antagonists) have already reached clinical testing while some others (like the antigastrin vaccine, H3-receptor ligands or gastrin-releasing peptide receptor antagonists) are still in preclinical development and need the proof of concept in human beings. |