Ignet

Gene Information

Gene symbol: CD63

Gene name: CD63 molecule

HGNC ID: 1692

Synonyms: ME491, TSPAN30

Related Genes

#	Gene Symbol	Number of hits
1	CCNB1	1 hits
2	CD200	1 hits
3	CD37	1 hits
4	CD53	1 hits
5	CD81	1 hits
6	CD86	1 hits
7	CD9	1 hits
8	CDK5R1	1 hits
9	CEACAM5	1 hits
10	CTSD	1 hits
11	ERBB2	1 hits
12	HLA-A	1 hits
13	HSP90AA1	1 hits
14	HSPA1A	1 hits
15	ICAM1	1 hits
16	IL2	1 hits
17	ITGAM	1 hits
18	LAMP1	1 hits
19	LAMP3	1 hits
20	MBP	1 hits
21	MLANA	1 hits
22	MUC1	1 hits
23	S100A1	1 hits
24	TP53	1 hits
25	TSPAN32	1 hits
26	TSPAN8	1 hits
27	UPK1B	1 hits
28	WARS	1 hits

Related Sentences

#	PMID	Sentence
1	1281197	To date there are 13 members including ME491 (CD63, Pltgp40), CD9 (p23), TAPA-1, CD37, CD53, MRC OX-44, CO-029, MRP-1, L6, the gene product of TI-1, the target of mAb AD-1, SM23, and SJ23 (the Schistosoma japonicum homologue).
2	12379326	These particles contain antigen presenting molecules (MHC class I, MHC class II, and CD1), tetraspan molecules (CD9, CD63, CD81), adhesion molecules (CD11b and CD54), and costimulatory molecules (CD86); hence, providing them the necessary machinery required for generating a potent immune response [J.
3	12472671	Proteasome subunit alpha type 3 (PSMA3), transcription factor EC (TFEC) isoform and BTK region clone 2f10-rpi were transiently upregulated.
4	12472671	Tryptophanyl-tRNA synthetase and CD63 antigen were upregulated for at least 24 h.
5	12472671	Neuronal apoptosis inhibitory protein (NAIP) and transforming growth factor-beta-induced 68 kDa protein were downregulated.
6	12472671	By comparing the expression of NAIP with that of other members of the inhibitor of apoptosis protein (IAP) family and the Bcl-2 family, only NAIP was found to be strongly expressed in iDCs before stimulation by LPS.
7	12960315	Infiltration with both CD4(+) and CD8(+) T lymphocytes was significantly more extensive in tumors from experimental mice than in tumors from control mice.
8	12960315	CD63 was immunogenic in 2 of 13 melanoma patients, pointing to the potential of this Ag, combined with IL-2, as a vaccine for melanoma patients.
9	15155622	We assessed the maturation of the F. tularensis phagosome by examining its acquisition of the lysosome-associated membrane glycoproteins (LAMPs) CD63 and LAMP1 and the acid hydrolase cathepsin D.
10	15155622	Two to four hours after infection, vacuoles containing live F. tularensis cells acquired abundant staining for LAMPs but little or no staining for cathepsin D.
11	15155622	These results indicate that F. tularensis initially enters a nonacidified phagosome with LAMPs but without cathepsin D and that the phagosomal membrane subsequently becomes morphologically disrupted, allowing the bacteria to gain direct access to the macrophagic cytoplasm.
12	15542372	We analyzed MART-1, S-100, MBP, and CD63 for melanoma and p53, MUC1, cyclin B1, HER-2/neu, and CEA for breast cancer.
13	24146068	Exosomes were isolated and the typical exosomal protein markers, CD9, CD63, heat shock protein (Hsp) 70 and Hsp90, were found to be enriched in the exosomes derived from Rab27a‑overexpressing cells.
14	24146068	Subsequently, these exosomes were demonstrated to be capable of upregulating major histocompatibility complex class II molecules as well as the co-stimulatory molecules CD80 and CD86 on dendritic cells (DCs), suggesting that more potent maturation of DCs was induced.
15	24269592	A subgroup of such microvesicles is called exosomes and is described in blood as 30 to 100 nm in diameter and as spherical to cup-shaped nanoparticles with specific surface molecular characteristics (eg, expression of the tetraspanins CD9, CD81, and CD63).
16	25769915	Molecular characterization of CD9 and CD63, two tetraspanin family members expressed in trout B lymphocytes.
17	25769915	In the current study, we have identified two novel tetraspanin members in rainbow trout (Oncorhynchus mykiss), homologs to mammalian CD9 and CD63.
18	25769915	Throughout the early life cycle stages, CD9 mRNA levels significantly increased after first feeding, whereas CD63 transcription remained constant during all the developmental stages analyzed.
19	25769915	In response to an experimental bath infection with viral hemorrhagic septicemia virus (VHSV), CD9 transcription was down-regulated in the gills, while CD63 mRNA levels were down-regulated in the head kidney.
20	25769915	Molecular characterization of CD9 and CD63, two tetraspanin family members expressed in trout B lymphocytes.
21	25769915	In the current study, we have identified two novel tetraspanin members in rainbow trout (Oncorhynchus mykiss), homologs to mammalian CD9 and CD63.
22	25769915	Throughout the early life cycle stages, CD9 mRNA levels significantly increased after first feeding, whereas CD63 transcription remained constant during all the developmental stages analyzed.
23	25769915	In response to an experimental bath infection with viral hemorrhagic septicemia virus (VHSV), CD9 transcription was down-regulated in the gills, while CD63 mRNA levels were down-regulated in the head kidney.
24	25769915	Molecular characterization of CD9 and CD63, two tetraspanin family members expressed in trout B lymphocytes.
25	25769915	In the current study, we have identified two novel tetraspanin members in rainbow trout (Oncorhynchus mykiss), homologs to mammalian CD9 and CD63.
26	25769915	Throughout the early life cycle stages, CD9 mRNA levels significantly increased after first feeding, whereas CD63 transcription remained constant during all the developmental stages analyzed.
27	25769915	In response to an experimental bath infection with viral hemorrhagic septicemia virus (VHSV), CD9 transcription was down-regulated in the gills, while CD63 mRNA levels were down-regulated in the head kidney.
28	25769915	Molecular characterization of CD9 and CD63, two tetraspanin family members expressed in trout B lymphocytes.
29	25769915	In the current study, we have identified two novel tetraspanin members in rainbow trout (Oncorhynchus mykiss), homologs to mammalian CD9 and CD63.
30	25769915	Throughout the early life cycle stages, CD9 mRNA levels significantly increased after first feeding, whereas CD63 transcription remained constant during all the developmental stages analyzed.
31	25769915	In response to an experimental bath infection with viral hemorrhagic septicemia virus (VHSV), CD9 transcription was down-regulated in the gills, while CD63 mRNA levels were down-regulated in the head kidney.