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Gene Information
Gene symbol: CD74
Gene name: CD74 molecule, major histocompatibility complex, class II invariant chain
HGNC ID: 1697
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD1D | 1 hits |
| 2 | CD4 | 1 hits |
| 3 | CD8A | 1 hits |
| 4 | CLIP1 | 1 hits |
| 5 | MIF | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 24205828 | MHCII and CD1d molecules associate with a conserved intracellular chaperone, CD74, also known as invariant chain. |
| 2 | 24205828 | In contrast, virus-induced disruptions in CD1d-mediated antigen presentation persisted even with sustained CD74 expression. |
| 3 | 24205828 | MHCII and CD1d molecules associate with a conserved intracellular chaperone, CD74, also known as invariant chain. |
| 4 | 24205828 | In contrast, virus-induced disruptions in CD1d-mediated antigen presentation persisted even with sustained CD74 expression. |
| 5 | 24583184 | Oos-MIF-1 was localised to the hypodermis/muscle, reproductive tract and intestine, but not to the cuticle. rOos-MIF-1.1, but not rOos-MIF-1.1P1G, was able to specifically bind to human CD74, a MIF cell surface receptor, with an affinity comparable with human MIF. |
| 6 | 24781998 | Here, we designed two Ii mutants, based on evidence that the invariant chain (Ii, also named CD74) binds newly synthesized MHC class I molecules with the class II-associated invariant chain peptide (CLIP) region of Ii, which occupies the peptide-binding groove. |
| 7 | 24945248 | The orthodox role of the invariant chain (CD74; Ii) is in antigen presentation to CD4+ T cells, but enhanced CD8+ T cells responses have been reported after vaccination with vectored viral vaccines encoding a fusion of Ii to the antigen of interest. |
| 8 | 24945248 | Following single or heterologous prime-boost vaccination of mice with a recombinant chimpanzee adenovirus vector, ChAd63, or recombinant modified vaccinia virus Ankara (MVA), higher frequencies of antigen-specific CD4+ and CD8+ T cells were observed, with the largest increases observed following a ChAd63-MVA heterologous prime-boost regimen. |