- About
- Home
- Introduction
- Statistics
- Programs
- Dignet
- Gene
- GenePair
- BioSummarAI
- Help & Docs
- Documents
- Help
- FAQs
- Links
- Acknowledge
- Disclaimer
- Contact Us
Gene Information
Gene symbol: CDC37
Gene name: cell division cycle 37 homolog (S. cerevisiae)
HGNC ID: 1735
Synonyms: P50CDC37
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | AZI2 | 1 hits |
| 2 | HSP90AA1 | 1 hits |
| 3 | SRC | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 25691576 | 5-Azacytidine-induced protein 2 (AZI2) is a TNF receptor (TNFR)-associated factor family member-associated NF-κB activator-binding kinase 1-binding protein that regulates the production of IFNs. |
| 2 | 25691576 | We revealed that the higher longevity of AZI2-deficient osteoclasts is due to an augmented activation of proto-oncogene tyrosine-protein kinase Src (c-Src), which is a critical player in osteoclast survival. |
| 3 | 25691576 | We found that AZI2 inhibits c-Src activity by regulating the activation of heat shock protein 90 (Hsp90), a chaperone involved in c-Src dephosphorylation. |
| 4 | 25691576 | Furthermore, we demonstrated that AZI2 indirectly inhibits c-Src by interacting with the Hsp90 co-chaperone Cdc37. |
| 5 | 25691576 | Strikingly, administration of a c-Src inhibitor markedly prevented bone loss in AZI2 knock-out mice. |