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Gene Information
Gene symbol: CDH5
Gene name: cadherin 5, type 2 (vascular endothelium)
HGNC ID: 1764
Synonyms: 7B4, CD144
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CDH17 | 1 hits |
| 2 | CDKN1A | 1 hits |
| 3 | DNMT1 | 1 hits |
| 4 | IL6 | 1 hits |
| 5 | IL8 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 20810819 | Cellular responses were assessed by investigating molecular changes at cell-cell junctions and by determining levels of secreted IL-6, IL-8, and vascular endothelial growth factor (VEGF) in the culture medium. |
| 2 | 20810819 | These barrier changes were associated with disruption of junctional vascular endothelial cadherin (VE-cadherin) and F-actin and an increase in endothelial secretion of IL-6 and IL-8. |
| 3 | 21497630 | As a strictly endothelial-specific adhesion molecule, vascular endothelial cadherin (VE-cadherin, VE-cad) is a promising anti-angiogenesis target. |
| 4 | 22359217 | Four chemicals reported to up-regulate E-cadherin were screened for their ability to counteract E6 repression of surface E-cadherin. 5-Aza-2'-deoxycytidine (AzaDC), a DNA methyltransferase inhibitor, and Indole-3-carbinol (I3C), reported to increase E-cadherin through a p21(Waf1/Cip1)-dependent mechanism, had low cytotoxicity and increased or restored E-cadherin expression and adhesive function in HPV16 E6 expressing HCT116 cells. |