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Gene Information
Gene symbol: CENPF
Gene name: centromere protein F, 350/400kDa (mitosin)
HGNC ID: 1857
Synonyms: hcp-1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CYCSP52 | 1 hits |
| 2 | CYCSP53 | 1 hits |
| 3 | CYCSP6 | 1 hits |
| 4 | NCAPD3 | 1 hits |
| 5 | PRMT1 | 1 hits |
| 6 | PTPN6 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 21300775 | Recombinant Hcp2 protected 80% of mice against a lethal challenge with K96243, while recombinant Hcp1, Hcp3, and Hcp6 protected 50% of mice against challenge. |
| 2 | 21300775 | Hcp6 was the only Hcp constitutively produced by B. pseudomallei in vitro; however, it was not exported to the extracellular milieu. |
| 3 | 24379895 | Immunization with recombinant B. mallei Hcp1 (type VI secreted/structural protein), BimA (autotransporter protein), BopA (type III secreted protein), and B. pseudomallei LolC (ABC transporter protein) generated significant protection against lethal inhaled B. mallei ATCC23344 and B. pseudomallei 1026b challenge. |
| 4 | 25194998 | AuNPs were covalently coupled with one of three different protein carriers (TetHc, Hcp1 and FliC) followed by conjugation to LPS purified from a non-virulent clonal relative, B. thailandensis. |
| 5 | 25648885 | Extended loop region of Hcp1 is critical for the assembly and function of type VI secretion system in Burkholderia pseudomallei. |
| 6 | 25648885 | Our structural study reveals that Hcp1 forms hexameric rings similar to the other Hcp homologs but has an extended loop (Asp40-Arg56) that deviates significantly in position compared to other Hcp structures and may act as a key contact point between adjacent hexameric rings. |
| 7 | 25648885 | Moreover, infection with a bacterial mutant containing in situ substitution of these hcp1 residues abolishes Hcp1 secretion inside infected cells and MNGC formation. |
| 8 | 25648885 | Extended loop region of Hcp1 is critical for the assembly and function of type VI secretion system in Burkholderia pseudomallei. |
| 9 | 25648885 | Our structural study reveals that Hcp1 forms hexameric rings similar to the other Hcp homologs but has an extended loop (Asp40-Arg56) that deviates significantly in position compared to other Hcp structures and may act as a key contact point between adjacent hexameric rings. |
| 10 | 25648885 | Moreover, infection with a bacterial mutant containing in situ substitution of these hcp1 residues abolishes Hcp1 secretion inside infected cells and MNGC formation. |
| 11 | 25648885 | Extended loop region of Hcp1 is critical for the assembly and function of type VI secretion system in Burkholderia pseudomallei. |
| 12 | 25648885 | Our structural study reveals that Hcp1 forms hexameric rings similar to the other Hcp homologs but has an extended loop (Asp40-Arg56) that deviates significantly in position compared to other Hcp structures and may act as a key contact point between adjacent hexameric rings. |
| 13 | 25648885 | Moreover, infection with a bacterial mutant containing in situ substitution of these hcp1 residues abolishes Hcp1 secretion inside infected cells and MNGC formation. |