- About
- Home
- Introduction
- Statistics
- Programs
- Dignet
- Gene
- GenePair
- BioSummarAI
- Help & Docs
- Documents
- Help
- FAQs
- Links
- Acknowledge
- Disclaimer
- Contact Us
Gene Information
Gene symbol: CIDX
Gene name: combined immunodeficiency, X-linked
HGNC ID: 1978
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ADA | 1 hits |
| 2 | CD4 | 1 hits |
| 3 | CD8A | 1 hits |
| 4 | NCF2 | 1 hits |
| 5 | ZAP70 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 8807512 | Their diagnoses were: chemotaxis defect, cellular immunodeficiency, combined immunodeficiency and chronic granulomatous disease (CGD). |
| 2 | 25842197 | [Adenosine deaminase 1 deficiency, an inborn error of metabolism underlying a severe form of combined immunodeficiency]. |
| 3 | 26187144 | SYK expression endows human ZAP70-deficient CD8 T cells with residual TCR signaling. |
| 4 | 26187144 | Autosomal recessive human ZAP70 deficiency is a rare cause of combined immunodeficiency (CID) characterized by defective CD4 T cells and profound CD8 T cell lymphopenia. |
| 5 | 26187144 | In contrast to CD4 T cells, the majority of the few CD8 T cells showed expression of the ZAP70-related tyrosine kinase SYK that correlated with residual TCR signaling including calcium flux and degranulation. |
| 6 | 26187144 | Our findings highlight the differential requirements of ZAP70 and SYK during thymic development, peripheral homeostasis as well as effector functions of CD4 and CD8 T cells. |