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Gene Information

Gene symbol: CLDN4

Gene name: claudin 4

HGNC ID: 2046

Synonyms: CPE-R, WBSCR8, hCPE-R

Related Genes

#	Gene Symbol	Number of hits
1	CLDN1	1 hits
2	OCLN	1 hits

Related Sentences

#	PMID	Sentence
1	25268493	The inner foreskin of healthy males at risk of HIV infection harbors epithelial CD4+ CCR5+ cells and has features of an inflamed epidermal barrier.
2	25268493	However, multiple suprabasal tight junction differences were identified: 1) inner foreskin stratum corneum was thinner than outer (p = 0.035); 2) claudin 1 had extended membrane-bound localization throughout inner epidermis stratum spinosum (p = 0.035); 3) membrane-bound claudin 4 was absent from inner foreskin stratum granulosum (p = 0.035); and 4) occludin had increased membrane deposition in inner foreskin stratum granulosum (p = 0.042) versus outer.
3	25268493	A setting of inflammation was further supported by inner foreskin epithelial explant cultures secreting higher levels of GM-CSF (p = 0.029), IP-10 (p = 0.035) and RANTES (p = 0.022) than outer foreskin, and also containing an increased density of CCR5+ and CD4+ CCR5+ cells (p = 0.022).