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Gene Information
Gene symbol: CLEC2B
Gene name: C-type lectin domain family 2, member B
HGNC ID: 2053
Synonyms: AICL, HP10085
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CLEC12A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16239426 | Dendritic-cell-associated C-type lectin 2 (DCAL-2) alters dendritic-cell maturation and cytokine production. |
| 2 | 16239426 | DCAL-2 is a CLR with a cytosolic immunoreceptor tyrosine-based inhibitory motif (ITIM), which is restricted to immature DCs (iDCs), monocytes, and CD1a+ DCs. |
| 3 | 16239426 | While anti-DCAL-2 did not induce iDCs to mature, it did up-regulate CCR7 expression and IL-6 and IL-10 production. |
| 4 | 16239426 | DCAL-2 signals augmented DC maturation induced by LPS or zymosan, increasing both CCR7 and DC-LAMP expression. |
| 5 | 16239426 | DCAL-2 ligation also suppressed the ability of TLR-matured DCs to induce IFN-gamma-secreting Th1 cells but augmented the capacity of CD40L-matured DCs to polarize naive T cells into Th1 cells. |