- About
- Home
- Introduction
- Statistics
- Programs
- Dignet
- Gene
- GenePair
- BioSummarAI
- Help & Docs
- Documents
- Help
- FAQs
- Links
- Acknowledge
- Disclaimer
- Contact Us
Gene Information
Gene symbol: CSNK2A1
Gene name: casein kinase 2, alpha 1 polypeptide
HGNC ID: 2457
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | DDX58 | 1 hits |
| 2 | IRF3 | 1 hits |
| 3 | PDIK1L | 1 hits |
| 4 | TBK1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15280222 | Many of the amino acid replacements were associated with the emergence of novel (or alternative) myristylation and casein kinase II (CKII) phosphorylation sites. |
| 2 | 25810395 | Casein kinase II controls TBK1/IRF3 activation in IFN response against viral infection. |
| 3 | 25810395 | In this study, we report that protein kinase CK2 serves as a key component controlling TBK1 and IRF3 activation in IFN-inducing TLR, RIG-I-like receptors, and cGAS/STING signaling pathways. |
| 4 | 25810395 | Moreover, PP2A was identified as one of the intermediate phosphatases responsible for CK2-regulated IFN response, suggesting that CK2 may regulate TBK1 and IRF3 activation indirectly. |
| 5 | 25810395 | Taken together, our results identify CK2 as a novel regulator of TBK1 and IRF3 and suggest that targeting CK2 by small molecular inhibitor may be a viable approach to prevent and treat viral infections. |