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Gene Information
Gene symbol: CXCL16
Gene name: chemokine (C-X-C motif) ligand 16
HGNC ID: 16642
Synonyms: SR-PSOX, CXCLG16, SRPSOX
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CCL17 | 1 hits |
| 2 | CCL18 | 1 hits |
| 3 | CCL19 | 1 hits |
| 4 | CCL2 | 1 hits |
| 5 | CCL22 | 1 hits |
| 6 | CCL23 | 1 hits |
| 7 | CCL24 | 1 hits |
| 8 | CCL27 | 1 hits |
| 9 | CCL3 | 1 hits |
| 10 | CCL4 | 1 hits |
| 11 | CXCL3 | 1 hits |
| 12 | CXCL5 | 1 hits |
| 13 | CXCR6 | 1 hits |
| 14 | IL10 | 1 hits |
| 15 | IL18 | 1 hits |
| 16 | IL8 | 1 hits |
| 17 | PPBP | 1 hits |
| 18 | SPP1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19450895 | Targeted knock down of CCL22 and CCL17 by siRNA during DC differentiation and maturation affects the recruitment of T subsets. |
| 2 | 19450895 | Using the recently developed chemokine protein arrays, we analyzed 38 chemokines associated with monocyte-derived DC (MoDC), including the CC family (CCL2, CCL3, CCL4, CCL17, CCL18, CCL22, CCL23, CCL24, CCL27) and the CXC family (CXCL3, CXCL5, CXCL7, CXCL8, CXCL16) chemokines. |
| 3 | 19450895 | Our results indicate that MoDC largely inherit the chemokines constitutively expressed by monocytes, with a significant induction of CCL17, CCL22 and CCL23. |
| 4 | 19450895 | Spent culture supernatant collected from MoDC exhibited chemotatic abilities to activate CD4(+), CD8(+), and CD25(+) Foxp3(+) regulatory T cells (Tregs). |
| 5 | 19450895 | Selective knock down of CCL22 and CCL17 expression by siRNA decreased the ratios of CD4(+) to CD8(+), as well as the frequency of Tregs recruited by MoDC. |
| 6 | 21628524 | Here we report that intranasal immunization with adenovirus-85A induces expression of the chemokine receptor CXCR6 on lung CD8 T lymphocytes, which is maintained for at least 3 months. |
| 7 | 21628524 | Upregulation of CXCR6 is accompanied by a transient elevation of serum CXCL16 after intranasal immunization, and lung cells cultured ex vivo from mice immunized intranasally show increased production of CXCL16. |
| 8 | 21628524 | We conclude that expression of CXCR6 on lung T lymphocytes is a correlate of local protective immunity against Mycobacterium tuberculosis after intranasal immunization and that CXCR6 and CXCL16 play an important role in the localization of T cells within lung tissue and the bronchoalveolar lavage-recoverable compartment. |
| 9 | 21628524 | Here we report that intranasal immunization with adenovirus-85A induces expression of the chemokine receptor CXCR6 on lung CD8 T lymphocytes, which is maintained for at least 3 months. |
| 10 | 21628524 | Upregulation of CXCR6 is accompanied by a transient elevation of serum CXCL16 after intranasal immunization, and lung cells cultured ex vivo from mice immunized intranasally show increased production of CXCL16. |
| 11 | 21628524 | We conclude that expression of CXCR6 on lung T lymphocytes is a correlate of local protective immunity against Mycobacterium tuberculosis after intranasal immunization and that CXCR6 and CXCL16 play an important role in the localization of T cells within lung tissue and the bronchoalveolar lavage-recoverable compartment. |
| 12 | 22426325 | At the injection site, 594 genes were differentially expressed, including up-regulation of the cytokines osteopontin (SPP1), IL-10 and IL-18 and the chemokines CCL2, CCL19 and CXCL16. |
| 13 | 22426325 | Of the 362 genes differentially expressed in the lymph node, IL-1β and CXCL11 were up-regulated whereas IL18, CCL15 and CXCL12 were down-regulated. |
| 14 | 22426325 | ISCOM-Matrix also modulated genes for pattern recognition receptors at the injection site (TLR2, TLR4, MRC1, PTX3, LGALS3) and in the lymph node (TLR4, RIG-I, MDA5, OAS1, EIF2AK2, LGALS3). |