Ignet

Gene Information

Gene symbol: CXCL3

Gene name: chemokine (C-X-C motif) ligand 3

HGNC ID: 4604

Synonyms: SCYB3, GROg, MIP-2b, CINC-2b

Related Genes

#	Gene Symbol	Number of hits
1	C5AR1	1 hits
2	CCL1	1 hits
3	CCL17	1 hits
4	CCL18	1 hits
5	CCL2	1 hits
6	CCL22	1 hits
7	CCL23	1 hits
8	CCL24	1 hits
9	CCL27	1 hits
10	CCL3	1 hits
11	CCL4	1 hits
12	CD40LG	1 hits
13	CSF2	1 hits
14	CTLA4	1 hits
15	CXCL1	1 hits
16	CXCL16	1 hits
17	CXCL2	1 hits
18	CXCL5	1 hits
19	CXCL9	1 hits
20	FOXP3	1 hits
21	IL10	1 hits
22	IL2	1 hits
23	IL8	1 hits
24	LTA	1 hits
25	PDCD1	1 hits
26	PPBP	1 hits
27	TNF	1 hits

Related Sentences

#	PMID	Sentence
1	19450895	Targeted knock down of CCL22 and CCL17 by siRNA during DC differentiation and maturation affects the recruitment of T subsets.
2	19450895	Using the recently developed chemokine protein arrays, we analyzed 38 chemokines associated with monocyte-derived DC (MoDC), including the CC family (CCL2, CCL3, CCL4, CCL17, CCL18, CCL22, CCL23, CCL24, CCL27) and the CXC family (CXCL3, CXCL5, CXCL7, CXCL8, CXCL16) chemokines.
3	19450895	Our results indicate that MoDC largely inherit the chemokines constitutively expressed by monocytes, with a significant induction of CCL17, CCL22 and CCL23.
4	19450895	Spent culture supernatant collected from MoDC exhibited chemotatic abilities to activate CD4(+), CD8(+), and CD25(+) Foxp3(+) regulatory T cells (Tregs).
5	19450895	Selective knock down of CCL22 and CCL17 expression by siRNA decreased the ratios of CD4(+) to CD8(+), as well as the frequency of Tregs recruited by MoDC.
6	20826612	The concentrations of several chemoattractants for neutrophils (CXCL1, CXCL2, CXCL3, CXCL8, and C5a) increased in milk after challenge, and the highest increases followed challenge with the combination of MDP and LTA.
7	20826612	Nucleotide-binding oligomerization domain 2 (NOD2), a major sensor of MDP, was expressed (mRNA) in bovine mammary tissue and by bMEpC in culture.
8	20826612	The production of interleukin-8 (IL-8) following the stimulation of bMEpC by LTA and MDP was dependent on the activation of NF-κB.
9	20826612	LTA-induced IL-8 production did not depend on platelet-activating factor receptor (PAFR), as the PAFR antagonist WEB2086 was without effect.
10	20826612	Although the levels of expression of the inflammatory cytokines tumor necrosis factor alpha (TNF-α) and IL-1β were increased by LTA and MDP at the mRNA level, no protein could be detected in the bMEpC culture supernatant.
11	20826612	Overall, this study indicates that the TLR2 and NOD2 pathways could cooperate to trigger an innate immune response to S. aureus mastitis.
12	23267892	[Prediction of WT1/MUC1 peptide dendritic cell therapy responders by quantification of ex vivo induced mRNA in whole blood].
13	23267892	To challenge this classic problem, we quantified 17 different leukocyte function-associated mRNAs( IFN-γ,TNFSF1, TNFSF2, TNFSF5, IL-10, TGF β,CTLA4, PD1, FOXP3, GMCSF, VEGF, IL-8, CCL8, CXCL3, and IL-2) in whole blood after ex vivo stimulation with 7 different agents(PHA, HAG, zymosan, IFN-γ,rIL-2, aTCR, and picibanil) to activate various subsets of leukocytes.
14	23267892	The clinical outcomes for WT1 peptide-and/or MUC1 peptide-pulsed dendritic cell therapy for advanced cancer (n=26) were CR+PR, 4 cases; SD, 9 cases; and PD, 13 cases.
15	24198818	Specific chemokines, such as CXCL3/MIP1α as well as CCL1/I-309 and CXCL9/Mig, attract T cells to the myocardium and valves, respectively.