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Gene Information

Gene symbol: CXCL5

Gene name: chemokine (C-X-C motif) ligand 5

HGNC ID: 10642

Synonyms: ENA-78

Related Genes

# Gene Symbol Number of hits
1 CCL17 1 hits
2 CCL18 1 hits
3 CCL2 1 hits
4 CCL22 1 hits
5 CCL23 1 hits
6 CCL24 1 hits
7 CCL27 1 hits
8 CCL3 1 hits
9 CCL4 1 hits
10 CXCL16 1 hits
11 CXCL3 1 hits
12 IL10 1 hits
13 IL8 1 hits
14 PPBP 1 hits

Related Sentences

# PMID Sentence
1 19450895 Targeted knock down of CCL22 and CCL17 by siRNA during DC differentiation and maturation affects the recruitment of T subsets.
2 19450895 Using the recently developed chemokine protein arrays, we analyzed 38 chemokines associated with monocyte-derived DC (MoDC), including the CC family (CCL2, CCL3, CCL4, CCL17, CCL18, CCL22, CCL23, CCL24, CCL27) and the CXC family (CXCL3, CXCL5, CXCL7, CXCL8, CXCL16) chemokines.
3 19450895 Our results indicate that MoDC largely inherit the chemokines constitutively expressed by monocytes, with a significant induction of CCL17, CCL22 and CCL23.
4 19450895 Spent culture supernatant collected from MoDC exhibited chemotatic abilities to activate CD4(+), CD8(+), and CD25(+) Foxp3(+) regulatory T cells (Tregs).
5 19450895 Selective knock down of CCL22 and CCL17 expression by siRNA decreased the ratios of CD4(+) to CD8(+), as well as the frequency of Tregs recruited by MoDC.
6 25394503 The vaccine also reduced the number of MDSCs in the tumor microenvironment through the downregulation of monocyte chemoattractant protein 1, interleukin-10, CXCL5 and arginase II, factors important for MDSC expansion.