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Gene Information
Gene symbol: CYP19A1
Gene name: cytochrome P450, family 19, subfamily A, polypeptide 1
HGNC ID: 2594
Synonyms: ARO, P-450AROM, CPV1, ARO1, CYAR, aromatase
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ERBB2 | 1 hits |
| 2 | ESR1 | 1 hits |
| 3 | PTGS2 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 14998568 | Recent developments have included a series of new endocrine therapies such as pure anti-oestrogens and selective oestrogen receptor modulators, and trials are in progress to determine their role in the sequence of therapies given the first-line role now occupied by the aromatase inhibitors. |
| 2 | 15788636 | They have also highlighted the importance of elucidating the pharmacodynamic interactions between established therapies for breast cancer, such as tamoxifen, aromatase inhibitors, chemotherapy, the HER-2/neu-specific monoclonal antibody trastuzumab (Herceptin), and breast cancer vaccines. |
| 3 | 15788636 | The first strategies targeting the negative influence of CD4(+)CD25(+)T regulatory cells and the CTLA-4 signaling pathway are just entering clinical testing in combination with tumor vaccines. |
| 4 | 23918793 | There is growing evidence that many of the most promising cancer chemoprevention agents including aspirin, COX-2 inhibitors, aromatase inhibitors, and bisphosphonates mediate their effects, in part, by enhancing immunosurveillance and reversing the immune evasive mechanisms that premalignant lesions use. |