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Gene Information

Gene symbol: CYP1A1

Gene name: cytochrome P450, family 1, subfamily A, polypeptide 1

HGNC ID: 2595

Synonyms: P450DX, P1-450, P450-C, CP11

Related Genes

# Gene Symbol Number of hits
1 CD8A 1 hits
2 CYP1B1 1 hits
3 CYP2B6 1 hits
4 CYP2C19 1 hits
5 FABP1 1 hits
6 SLC5A1 1 hits
7 TBXAS1 1 hits

Related Sentences

# PMID Sentence
1 2143687 In a comparison of patients receiving MCV alone to MCV + CYP 300 mg/m2 phenotypic analysis of lymphocyte subsets showed significant (P = 0.03) reduction in the CD8+CD11B+ (suppressor) cells of the latter group.
2 15207781 Repeated immunization with plasmid DNA formulated in poly(lactide-co-glycolide) microparticles is well tolerated and stimulates durable T cell responses to the tumor-associated antigen cytochrome P450 1B1.
3 15207781 Cytochrome P450 CYP1B1 (CYP1B1) is a member of the CYP1 P450 enzyme family that is overexpressed in a variety of solid tumors.
4 15207781 Immunization of HLA-A2/Kb transgenic mice with human CYP1B1 encoding plasmid DNA formulated in poly(lactide-co-glycolide) (PLG) microparticles elicits CD8+ T cells that respond to human CYP1B1-positive target cells.
5 15694700 Drug biotransformations are controlled in the body by tissue-differentiated choice of a selection of the induced and constitutive 57 isoforms of the human cytochromes P450 (CYP).
6 16555997 Cytochrome P450 1B1: a novel anticancer therapeutic target.
7 16555997 Cytochrome P450 (CYP)1B1 is overexpressed in tumor cells and is also recognized as a biomarker of the tumor phenotype.
8 24990552 Coleus forskohlii extract attenuates the hypoglycemic effect of tolbutamide in vivo via a hepatic cytochrome P450-mediated mechanism.
9 24990552 In particular, increases in activity and protein expression were noted for the CYP2B, CYP2C, and CYP3A subtypes.
10 24990552 These results indicate that CFE induced hepatic CYPs in rats and attenuated the hypoglycemic action of tolbutamide via a hepatic CYP2C-mediated mechanism.
11 25049616 LPS and CYP increased intestinal enzyme activity, relative expression of SGLT-1, CaBP-D28k and L-FABP mRNAs (p<0.05).