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Gene Information
Gene symbol: CYP2C19
Gene name: cytochrome P450, family 2, subfamily C, polypeptide 19
HGNC ID: 2621
Synonyms: P450IIC19, CPCJ
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CYP1A1 | 1 hits |
| 2 | CYP2B6 | 1 hits |
| 3 | CYP3A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 22484351 | Improvac does not modify the expression and activities of the major drug metabolizing enzymes cytochrome P450 3A and 2C in pigs. |
| 2 | 22484351 | Additionally, we examined the mRNA expression of the two nuclear receptors pregnane X receptor (PXR) and constitutive androstane receptor (CAR), known to regulate CYP3A and 2C mRNA expression, respectively. |
| 3 | 22484351 | Activities of CYP3A and 2C were estimated as a rate of 7-benzyloxy-4-trifluoromethylcoumarin and 7-benzyloxyquinoline metabolism (CYP3A) and tolbutamide metabolism (CYP2C). |
| 4 | 24990552 | Coleus forskohlii extract attenuates the hypoglycemic effect of tolbutamide in vivo via a hepatic cytochrome P450-mediated mechanism. |
| 5 | 24990552 | In particular, increases in activity and protein expression were noted for the CYP2B, CYP2C, and CYP3A subtypes. |
| 6 | 24990552 | These results indicate that CFE induced hepatic CYPs in rats and attenuated the hypoglycemic action of tolbutamide via a hepatic CYP2C-mediated mechanism. |
| 7 | 24990552 | Coleus forskohlii extract attenuates the hypoglycemic effect of tolbutamide in vivo via a hepatic cytochrome P450-mediated mechanism. |
| 8 | 24990552 | In particular, increases in activity and protein expression were noted for the CYP2B, CYP2C, and CYP3A subtypes. |
| 9 | 24990552 | These results indicate that CFE induced hepatic CYPs in rats and attenuated the hypoglycemic action of tolbutamide via a hepatic CYP2C-mediated mechanism. |