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Gene Information
Gene symbol: CYP3A4
Gene name: cytochrome P450, family 3, subfamily A, polypeptide 4
HGNC ID: 2637
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CYP2B6 | 1 hits |
| 2 | EPHX1 | 1 hits |
| 3 | EPHX2 | 1 hits |
| 4 | IFNG | 1 hits |
| 5 | SCN1A | 1 hits |
| 6 | TBXAS1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 14615474 | This correlation supports in vitro findings of decreased CYP3A4 expression and activity with IFNgamma exposure. |
| 2 | 24125961 | Effects of EPHX1, SCN1A and CYP3A4 genetic polymorphisms on plasma carbamazepine concentrations and pharmacoresistance in Chinese patients with epilepsy. |
| 3 | 24125961 | In this study, we sought to investigate the effects of genetic polymorphisms of the microsomal epoxide hydrolase (EPHX1), the sodium channel α subunit type I (SCN1A) and the cytochrome P450 3A4 (CYP3A4) genes on plasma CBZ concentrations and pharmacoresistance in Chinese patients with epilepsy. |
| 4 | 24125961 | The EPHX1 c.337T>C, c.416A>G, SCN1A IVS5-91G>A or CYP3A4*1G polymorphisms were detected by polymerase chain reaction-restriction fragment length polymorphism approach or direct DNA sequencing in 83 Chinese patients treated with CBZ monotherapy. |
| 5 | 24125961 | There were no associations between all the studied genotypes involving EPHX1 c.337T>C, c.416A>G, SCN1A IVS5-91G>A or CYP3A4*1G polymorphisms and pharmacoresistance in this patient cohort. |
| 6 | 24125961 | Effects of EPHX1, SCN1A and CYP3A4 genetic polymorphisms on plasma carbamazepine concentrations and pharmacoresistance in Chinese patients with epilepsy. |
| 7 | 24125961 | In this study, we sought to investigate the effects of genetic polymorphisms of the microsomal epoxide hydrolase (EPHX1), the sodium channel α subunit type I (SCN1A) and the cytochrome P450 3A4 (CYP3A4) genes on plasma CBZ concentrations and pharmacoresistance in Chinese patients with epilepsy. |
| 8 | 24125961 | The EPHX1 c.337T>C, c.416A>G, SCN1A IVS5-91G>A or CYP3A4*1G polymorphisms were detected by polymerase chain reaction-restriction fragment length polymorphism approach or direct DNA sequencing in 83 Chinese patients treated with CBZ monotherapy. |
| 9 | 24125961 | There were no associations between all the studied genotypes involving EPHX1 c.337T>C, c.416A>G, SCN1A IVS5-91G>A or CYP3A4*1G polymorphisms and pharmacoresistance in this patient cohort. |