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Gene Information
Gene symbol: DEFB1
Gene name: defensin, beta 1
HGNC ID: 2766
Synonyms: HBD-1, DEFB-1, DEFB101, HBD1, BD1, MGC51822
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ART1 | 1 hits |
| 2 | ART3 | 1 hits |
| 3 | CAMP | 1 hits |
| 4 | DEFA1 | 1 hits |
| 5 | DEFB4 | 1 hits |
| 6 | TLR4 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 14734759 | Skin lesions of patients with AD, but not psoriasis, is deficient in the cathelicidin antimicrobial peptide (LL-37) and human beta-defensin-2 (HBD-2). |
| 2 | 14734759 | The Wyeth vaccine strain of vaccinia virus was incubated with varying concentrations of human (LL-37) and murine (CRAMP) cathelicidins, human alpha-defensin (HBD-1, HBD-2), and a control peptide. |
| 3 | 21865417 | We show here that RVFHbαP exerts an anti-inflammatory activity in hVECs, as suggested by the prevention of LPS-induced production of extracellular (supernatant) and intracellular (lysate) levels of cytokines (interleukin 6 [IL-6] and IL-1α) and chemokines (IL-8 and monocyte chemoattractant protein 1 [MCP-1]). |
| 4 | 21865417 | The demonstration of Toll-like receptor 4 (TLR4) and NF-κB expression in hVECs and the observations of RVFHbαP suppression of human β-defensin-1 (hBD1) mRNA expression further support the hypothesis of a genomic activity of RVFHbαP. |
| 5 | 22879887 | Cholera toxin (CT) from Vibrio cholerae and heat labile enterotoxin (LT) from Escherichia coli both modified the human α-defensin (HNP-1) and β- defensin-1 (HBD1), as efficiently as the mammalian mono-ADP-ribosyltransferase-1. |
| 6 | 22879887 | Pseudomonas aeruginosa exoenzyme S was inactive on both HNP-1 and HBD1. |
| 7 | 22879887 | Neisseria meningitidis NarE poorly recognized HNP-1 as a substrate but it was completely inactive on HBD1. |
| 8 | 22879887 | Cholera toxin (CT) from Vibrio cholerae and heat labile enterotoxin (LT) from Escherichia coli both modified the human α-defensin (HNP-1) and β- defensin-1 (HBD1), as efficiently as the mammalian mono-ADP-ribosyltransferase-1. |
| 9 | 22879887 | Pseudomonas aeruginosa exoenzyme S was inactive on both HNP-1 and HBD1. |
| 10 | 22879887 | Neisseria meningitidis NarE poorly recognized HNP-1 as a substrate but it was completely inactive on HBD1. |
| 11 | 22879887 | Cholera toxin (CT) from Vibrio cholerae and heat labile enterotoxin (LT) from Escherichia coli both modified the human α-defensin (HNP-1) and β- defensin-1 (HBD1), as efficiently as the mammalian mono-ADP-ribosyltransferase-1. |
| 12 | 22879887 | Pseudomonas aeruginosa exoenzyme S was inactive on both HNP-1 and HBD1. |
| 13 | 22879887 | Neisseria meningitidis NarE poorly recognized HNP-1 as a substrate but it was completely inactive on HBD1. |