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Gene Information
Gene symbol: DGKQ
Gene name: diacylglycerol kinase, theta 110kDa
HGNC ID: 2856
Synonyms: DAGK, DAGK7
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | PRKAR1A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 24778279 | We developed a retroviral CAR construct specific for the mouse fibroblast activation protein (FAP), comprising a single-chain Fv FAP [monoclonal antibody (mAb) 73.3] with the CD8α hinge and transmembrane regions, and the human CD3ζ and 4-1BB activation domains. |
| 2 | 24778279 | The antitumor effects could be augmented by multiple injections of the CAR T cells, by using CAR T cells with a deficiency in diacylglycerol kinase, or by combination with a vaccine. |
| 3 | 24778279 | In summary, inhibiting tumor growth by targeting tumor stroma with adoptively transferred CAR T cells directed to FAP can be safe and effective, suggesting that further clinical development of anti-human FAP-CAR is warranted. |