Gene Information
Gene symbol: DIABLO
Gene name: diablo, IAP-binding mitochondrial protein
HGNC ID: 21528
Synonyms: SMAC, DIABLO-S, FLJ25049, FLJ10537, DFNA64
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
18338832
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In the present study, we used attenuated S. typhimurium as a carrier to deliver a eukaryotic expression vector (pSNhTS) that contains the second mitochondria-derived activator of caspases (Smac) and tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) genes under the control of the hTERT promoter.
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2 |
18338832
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The results of in vitro experiments showed that Smac could enhance TRAIL-induced apoptosis in tumor cells and the hTERT promoter could drive specific gene expression in tumor cells, but not in normal cells.
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3 |
18338832
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/SNhTS was due to the synergistic antitumoral properties of Smac and TRAIL-recombinant proteins.
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