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Gene Information

Gene symbol: DIRAS3

Gene name: DIRAS family, GTP-binding RAS-like 3

HGNC ID: 687

Synonyms: NOEY2

Related Genes

#	Gene Symbol	Number of hits
1	CD8A	1 hits
2	HRAS	1 hits
3	MYC	1 hits
4	TP53	1 hits

Related Sentences

#	PMID	Sentence
1	10093040	Three out of 10 evaluable patients generated a mutant Ras specific CD4+ and/or CD8+ T-cell immune response.
2	10093040	The CD8+ cytotoxic cells specific for Gly to Val mutation at codon 12 were capable of lysing an HLA-A2-matched tumor cell line carrying the corresponding mutant but not the wild-type ras gene.
3	12056878	I show that the same model suggests that a cancer vaccine strategy that targets 'key' network elements, such as p53 or RAS gene products, is not the only effective strategy for a broadly effective anti-cancer therapy.
4	16196281	DCs were generated from mouse bone marrow in the presence of rmGM-CSF (3.3 ng/mL) and rmIL-4 (1.3 ng/mL) and detected by FACS, and then transfected with the recombinant adenovirus encoding mutant k-ras gene.
5	16196281	BmDCs highly expressed B7-1 (80%), B7-2 (77%), MHC II (70%), CD11c (65%), CD40 (70%) and CD54 (96%) with FACS, and no significant difference in the expression was observed before and after the transfection (P > 0.05).
6	16196281	The DCs transfected by mutant k-ras gene could significantly stimulate lymphocytes proliferation as compared with those transfected by Ad-c or non-modified DCs (P < 0.05).
7	16196281	DC vaccine transfected by mutant k-ras gene could induce CTL activity against Lewis lung cancer, but not against B16.
8	16196281	DCs were generated from mouse bone marrow in the presence of rmGM-CSF (3.3 ng/mL) and rmIL-4 (1.3 ng/mL) and detected by FACS, and then transfected with the recombinant adenovirus encoding mutant k-ras gene.
9	16196281	BmDCs highly expressed B7-1 (80%), B7-2 (77%), MHC II (70%), CD11c (65%), CD40 (70%) and CD54 (96%) with FACS, and no significant difference in the expression was observed before and after the transfection (P > 0.05).
10	16196281	The DCs transfected by mutant k-ras gene could significantly stimulate lymphocytes proliferation as compared with those transfected by Ad-c or non-modified DCs (P < 0.05).
11	16196281	DC vaccine transfected by mutant k-ras gene could induce CTL activity against Lewis lung cancer, but not against B16.
12	16196281	DCs were generated from mouse bone marrow in the presence of rmGM-CSF (3.3 ng/mL) and rmIL-4 (1.3 ng/mL) and detected by FACS, and then transfected with the recombinant adenovirus encoding mutant k-ras gene.
13	16196281	BmDCs highly expressed B7-1 (80%), B7-2 (77%), MHC II (70%), CD11c (65%), CD40 (70%) and CD54 (96%) with FACS, and no significant difference in the expression was observed before and after the transfection (P > 0.05).
14	16196281	The DCs transfected by mutant k-ras gene could significantly stimulate lymphocytes proliferation as compared with those transfected by Ad-c or non-modified DCs (P < 0.05).
15	16196281	DC vaccine transfected by mutant k-ras gene could induce CTL activity against Lewis lung cancer, but not against B16.
16	25302710	We generated a plasmid expressing both an activated human H-ras gene and murine c-myc gene and showed that 1 µg of this plasmid, pMSV-T24-H-ras/MSV-c-myc, was capable of inducing tumors in newborn NIH Swiss mice.
17	25302710	In this paper, we demonstrate that the newborn CD3 epsilon transgenic mouse, which is defective in both T-cell and NK-cell functions, can detect the oncogenic activity of 25 ng of the circular form of pMSV-T24-H-ras/MSV-c-myc.
18	25302710	To determine whether it can detect the oncogenic activity of cellular DNA derived from four human tumor-cell lines (HeLa, A549, HT-1080, and CEM), DNA (100 µg) was inoculated into newborn CD3 epsilon mice both in the presence of 1 µg of linear pMSV-T24-H-ras/MSV-c-myc as positive control and in its absence.