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Gene Information
Gene symbol: DKK1
Gene name: dickkopf 1 homolog (Xenopus laevis)
HGNC ID: 2891
Synonyms: SK, DKK-1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | ASF1A | 1 hits |
| 2 | BMP2 | 1 hits |
| 3 | CD274 | 1 hits |
| 4 | CD4 | 1 hits |
| 5 | CD8A | 1 hits |
| 6 | COL1A1 | 1 hits |
| 7 | FOXP3 | 1 hits |
| 8 | IL10 | 1 hits |
| 9 | MAGEA3 | 1 hits |
| 10 | TERT | 1 hits |
| 11 | TIMM8A | 1 hits |
| 12 | TNFRSF4 | 1 hits |
| 13 | TNFSF13B | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 22049519 | Furthermore, the addition of CpG as an adjuvant, or injection of B7H1-blocking or OX40-agonist Abs, further enhanced the therapeutic effects of the vaccine. |
| 2 | 22049519 | Mechanistic studies revealed that DKK1 vaccine elicited a strong DKK1- and tumor-specific CD4+ and CD8+ immune responses, and treatment with B7H1 or OX40 Abs significantly reduced the numbers of IL-10-expressing and Foxp3+ regulatory T cells in vaccinated mice. |
| 3 | 22215754 | First, immune-based therapies are being developed (eg, elotuzumab monoclonal antibody [MoAb]; CD138DM immunotoxin; MM cell-dendritic cell vaccines; CD138, CS-1, and XBP-1 peptide vaccines; anti-17 MoAb; and other treatments to overcome causes of immune dysfunction). |
| 4 | 22215754 | Moreover, agents targeting bone biology (eg, zoledronic acid, anti-DKK-1 MoAb, anti-B-cell activating factor MoAb and bortezomib, Btk inhibitor) show promise not only in preserving bone integrity but also against MM. |
| 5 | 24907907 | DKK1-derived peptides (DDPs) were added to BMP2-stimulated MC3T3-E1 preosteoblastic cells in vitro to evaluate inhibitory activity of DDPs in MC3T3-E1 cell differentiation. |
| 6 | 25195787 | Besides a comprehensive list of tumor antigens for T cell-based approaches, eight promising antigens, CS1, Dickkopf-1, HM1.24, Human telomerase reverse transcriptase, MAGE-A3, New York Esophageal-1, Receptor of hyaluronic acid mediated motility and Wilms' tumor gene 1, are described in detail to provide a background for potential clinical use. |
| 7 | 26075259 | Designation of a novel DKK1 multiepitope DNA vaccine and inhibition of bone loss in collagen-induced arthritic mice. |
| 8 | 26075259 | Furthermore, we optimized four B cell epitopes to design a novel DKK1 multiepitope DNA vaccine and evaluated its bone protective effects in collagen-induced arthritis (CIA), a mouse model of RA. |
| 9 | 26075259 | Designation of a novel DKK1 multiepitope DNA vaccine and inhibition of bone loss in collagen-induced arthritic mice. |
| 10 | 26075259 | Furthermore, we optimized four B cell epitopes to design a novel DKK1 multiepitope DNA vaccine and evaluated its bone protective effects in collagen-induced arthritis (CIA), a mouse model of RA. |