Ignet

Gene Information

Gene symbol: DYNC1H1

Gene name: dynein, cytoplasmic 1, heavy chain 1

HGNC ID: 2961

Synonyms: Dnchc1, HL-3, p22, DHC1

Related Genes

#	Gene Symbol	Number of hits
1	ALB	1 hits
2	CALR	1 hits
3	CCNH	1 hits
4	CD79A	1 hits
5	CD8A	1 hits
6	DCTN5	1 hits
7	DDX17	1 hits
8	FKBP5	1 hits
9	IFNG	1 hits
10	IL12A	1 hits
11	MAPK1	1 hits
12	PRR6	1 hits
13	PSMD9	1 hits
14	PTGES3	1 hits
15	RAD51	1 hits
16	TP53	1 hits
17	TUFM	1 hits
18	VHLL	1 hits

Related Sentences

#	PMID	Sentence
1	1372316	One of the two B.rfb+ gene clusters of a (P22-lysogenic) S. typhimurium strain with a tandem duplication of a chromosomal segment including hisD and B.rfb+ was replaced (by transduction) by a D.rfb+ gene cluster; the resulting strain was O1+ O4+ O5+ O9+ and stable as such after being made recA.
2	2241683	Purified MG proteins of 65 to 63 (p64) kilodaltons (kDa), and 26 and 24 (p26/24) kDa, and purified MS proteins of 53 (p53) kDa, 41 (p41) kDa, and 22 (p22) kDa were evaluated as potential antigens for an enzyme-linked immunosorbent assay (ELISA).
3	2241683	MS antigens p53 and p22 did not perform well.
4	2241683	Purified MG proteins of 65 to 63 (p64) kilodaltons (kDa), and 26 and 24 (p26/24) kDa, and purified MS proteins of 53 (p53) kDa, 41 (p41) kDa, and 22 (p22) kDa were evaluated as potential antigens for an enzyme-linked immunosorbent assay (ELISA).
5	2241683	MS antigens p53 and p22 did not perform well.
6	6305755	Because P22 did not react with polymerized albumin, the sequence of 55 amino acid residues in the pre-S region appeared to bear the receptor.
7	6781788	Hepatitis B Vaccine antigen, purified from HBs positive and HBe negative plasma, is constituted of well defined morphological particles, containing two major polypeptides P22 and P27, and without any trace of viral DNA.
8	7216495	Therefore, the two major polypeptides with molecular weights of 22,000 and 25,000 (P22 and P25, respectively) were isolated, adsorbed to an alum adjuvant, and used to immunize four nonimmune chimpanzees.
9	8500902	The major antigens incorporated into the immunostimulating complexes were the P30 and P22 antigens and an antigen with an approximate molecular weight of 6,000.
10	11599738	In re-analyses of sera for total immunoglobulins in ELISAs with recombinant antigens, reactions were most frequently recorded when outer-surface protein (Osp) F, protein (p)35, p37, p39 and p-41G (a flagellin component) were tested separately.
11	11599738	Sera from vaccinated dogs contained antibodies to OspA, OspB, p22, p37 and p41-G.
12	11599738	Therefore, serological reactions to OspF, p35 and p39 were the most important indicators of natural exposure to B. burgdorferi.
13	14980493	Neutralizing antibodies to African swine fever virus proteins p30, p54, and p72 are not sufficient for antibody-mediated protection.
14	14980493	Virus neutralizing epitopes have been identified on three viral proteins, p30, p54, and p72.
15	14980493	To evaluate the role(s) of these proteins in protective immunity, pigs were immunized with baculovirus-expressed p30, p54, p72, and p22 from the pathogenic African swine fever virus (ASFV) isolate Pr4.
16	17108279	An immunogenic 22 kilodalton exported Mycobacterium avium subspecies paratuberculosis (MAP) lipoprotein (P22) was previously identified, and found to belong to the LppX/LprAFG family of mycobacterial lipoproteins.
17	17108279	Antibody recognition of P22, and interferon-gamma (IFN-gamma) responses in vitro using blood from a sheep vaccinated with Neoparasec, confirmed its immunogenicity.
18	17108279	Blood was collected at 4, 13 and 29 weeks post-immunization (p.i.) and tested for anti-P22 antibodies and P22-specific IFN-gamma production.
19	17108279	Recombinant P22 was able to stimulate significant IFN-gamma production in blood of P22-immunized sheep at 13 and 29 weeks p.i.
20	17108279	Recombinant P22 also elicited an IFN-gamma response in blood of sheep immunized with Neoparasec.
21	17108279	An immunogenic 22 kilodalton exported Mycobacterium avium subspecies paratuberculosis (MAP) lipoprotein (P22) was previously identified, and found to belong to the LppX/LprAFG family of mycobacterial lipoproteins.
22	17108279	Antibody recognition of P22, and interferon-gamma (IFN-gamma) responses in vitro using blood from a sheep vaccinated with Neoparasec, confirmed its immunogenicity.
23	17108279	Blood was collected at 4, 13 and 29 weeks post-immunization (p.i.) and tested for anti-P22 antibodies and P22-specific IFN-gamma production.
24	17108279	Recombinant P22 was able to stimulate significant IFN-gamma production in blood of P22-immunized sheep at 13 and 29 weeks p.i.
25	17108279	Recombinant P22 also elicited an IFN-gamma response in blood of sheep immunized with Neoparasec.
26	17108279	An immunogenic 22 kilodalton exported Mycobacterium avium subspecies paratuberculosis (MAP) lipoprotein (P22) was previously identified, and found to belong to the LppX/LprAFG family of mycobacterial lipoproteins.
27	17108279	Antibody recognition of P22, and interferon-gamma (IFN-gamma) responses in vitro using blood from a sheep vaccinated with Neoparasec, confirmed its immunogenicity.
28	17108279	Blood was collected at 4, 13 and 29 weeks post-immunization (p.i.) and tested for anti-P22 antibodies and P22-specific IFN-gamma production.
29	17108279	Recombinant P22 was able to stimulate significant IFN-gamma production in blood of P22-immunized sheep at 13 and 29 weeks p.i.
30	17108279	Recombinant P22 also elicited an IFN-gamma response in blood of sheep immunized with Neoparasec.
31	17108279	An immunogenic 22 kilodalton exported Mycobacterium avium subspecies paratuberculosis (MAP) lipoprotein (P22) was previously identified, and found to belong to the LppX/LprAFG family of mycobacterial lipoproteins.
32	17108279	Antibody recognition of P22, and interferon-gamma (IFN-gamma) responses in vitro using blood from a sheep vaccinated with Neoparasec, confirmed its immunogenicity.
33	17108279	Blood was collected at 4, 13 and 29 weeks post-immunization (p.i.) and tested for anti-P22 antibodies and P22-specific IFN-gamma production.
34	17108279	Recombinant P22 was able to stimulate significant IFN-gamma production in blood of P22-immunized sheep at 13 and 29 weeks p.i.
35	17108279	Recombinant P22 also elicited an IFN-gamma response in blood of sheep immunized with Neoparasec.
36	17108279	An immunogenic 22 kilodalton exported Mycobacterium avium subspecies paratuberculosis (MAP) lipoprotein (P22) was previously identified, and found to belong to the LppX/LprAFG family of mycobacterial lipoproteins.
37	17108279	Antibody recognition of P22, and interferon-gamma (IFN-gamma) responses in vitro using blood from a sheep vaccinated with Neoparasec, confirmed its immunogenicity.
38	17108279	Blood was collected at 4, 13 and 29 weeks post-immunization (p.i.) and tested for anti-P22 antibodies and P22-specific IFN-gamma production.
39	17108279	Recombinant P22 was able to stimulate significant IFN-gamma production in blood of P22-immunized sheep at 13 and 29 weeks p.i.
40	17108279	Recombinant P22 also elicited an IFN-gamma response in blood of sheep immunized with Neoparasec.
41	17466457	Here, we found serum collected from sheep immunized with Haemaphysalis qinghaiensis salivary gland extracts could detect two more protein bands with molecular weights of 22 and 37 kDa (P22 and P37) on Western blots of extracts of tick salivary glands than serum from tick infected animals.
42	17466457	Rabbit anti-H. qinghaiensis differential protein immune serum was then generated from P22 and P37 and was used to immunoscreen a cDNA library constructed from salivary glands, Malpighian tubules and ovaries of partially engorged H. qinghaiensis.
43	17466457	The predicted amino acid sequence of the Hq02 gene had high homology to some known myosin alkali light chain (MLC) proteins.
44	17466457	Here, we found serum collected from sheep immunized with Haemaphysalis qinghaiensis salivary gland extracts could detect two more protein bands with molecular weights of 22 and 37 kDa (P22 and P37) on Western blots of extracts of tick salivary glands than serum from tick infected animals.
45	17466457	Rabbit anti-H. qinghaiensis differential protein immune serum was then generated from P22 and P37 and was used to immunoscreen a cDNA library constructed from salivary glands, Malpighian tubules and ovaries of partially engorged H. qinghaiensis.
46	17466457	The predicted amino acid sequence of the Hq02 gene had high homology to some known myosin alkali light chain (MLC) proteins.
47	22465748	If animals were pretreated with a disparate VLP, P22 (a non-replicative bacteriophage capsid), before OVA-sHsp conjugate immunization, OVA-specific IgG1 responses were apparent already by 4 days after a single immunizing dose of conjugate in OVA-naïve mice.
48	22465748	Additionally, the mice pretreated with P22 produced high titer mucosal IgA, and isotype-switched OVA-specific serum IgG.
49	22465748	If animals were pretreated with a disparate VLP, P22 (a non-replicative bacteriophage capsid), before OVA-sHsp conjugate immunization, OVA-specific IgG1 responses were apparent already by 4 days after a single immunizing dose of conjugate in OVA-naïve mice.
50	22465748	Additionally, the mice pretreated with P22 produced high titer mucosal IgA, and isotype-switched OVA-specific serum IgG.
51	23251389	Wogonin induced calreticulin/annexin A1 exposure dictates the immunogenicity of cancer cells in a PERK/AKT dependent manner.
52	23251389	Here we demonstrated for the first time that wogonin elicits a potent antitumor immunity effect by inducing the translocation of calreticulin (CRT) and Annexin A1 to cell plasma membrane as well as the release of high-mobility group protein 1 (HMGB1) and ATP.
53	23251389	We found that wogonin-induced reactive oxygen species (ROS) production causes an endoplasmic reticulum (ER) stress response, including the phosphorylation of PERK (PKR-like endoplasmic reticulum kinase)/PKR (protein kinase R) and eIF2α (eukaryotic initiation factor 2α), which served as upstream signal for the activation of phosphoinositide 3-kinase (PI3K)/AKT, inducing calreticulin (CRT)/Annexin A1 cell membrane translocation.
54	23251389	P22/CHP, a Ca(2+)-binding protein, was associated with CRT and was required for CRT translocation to cell membrane.
55	23251389	In conclusion, the activation of PI3K pathway elicited by ER stress induced CRT/Annexin A1 translocation ("eat me" signal) and HMGB1 release, mediating wogonin-induced immunity of tumor cell vaccine.
56	23540530	Programmed encapsulation and sequestration of the conserved nucleoprotein (NP) from influenza on the interior of a VLP, derived from the bacteriophage P22, results in a vaccine that provides multistrain protection against 100 times lethal doses of influenza in an NP specific CD8+ T cell-dependent manner.
57	25856903	The surface antigens of T. gondii with the potential for application as antigens of diagnosis and vaccines have been studied extensively in recent years, especially for P43, P35, P30, P23 and P22.