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Gene Information
Gene symbol: EGR3
Gene name: early growth response 3
HGNC ID: 3240
Synonyms: PILOT
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | EGR2 | 1 hits |
| 2 | IL6 | 1 hits |
| 3 | IL8 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 23166773 | Previously, we had identified Egr-2 and Egr-3 as NF-AT-induced transcription factors which promote the inhibition of T cell activation. |
| 2 | 23166773 | Likewise, Spry1(Flox/Flox) Lck Cre CD8⁺ T cells display increased cytolytic activity. |
| 3 | 23166773 | Mechanistically, Spry1 acts at the level of PLC-γ promoting the inhibition of both Ca⁺⁺ induced NF-AT activation and MAP-kinase induced AP-1 activation while sparing NF-κB signaling. |
| 4 | 25633035 | Early Growth Response 3 regulates genes of inflammation and directly activates IL6 and IL8 expression in prostate cancer. |