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Gene Information
Gene symbol: ENG
Gene name: endoglin
HGNC ID: 3349
Synonyms: END, HHT1, CD105
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD4 | 1 hits |
| 2 | CD8A | 1 hits |
| 3 | CXCL9 | 1 hits |
| 4 | FASLG | 1 hits |
| 5 | FOSL1 | 1 hits |
| 6 | IFNG | 1 hits |
| 7 | IV | 1 hits |
| 8 | PECAM1 | 1 hits |
| 9 | TLR1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 12477432 | Co-immunization of rhesus macaques with plasmid vectors expressing IFN-gamma, GM-CSF, and SIV antigens enhances anti-viral humoral immunity but does not affect viremia after challenge with highly pathogenic virus. |
| 2 | 12477432 | To investigate the adjuvant capacity of granulocyte-macrophage colony-stimulating factor (GM-CSF) and interferon (IFN-gamma), we cloned these rhesus cytokines into a mammalian expression vector. |
| 3 | 12477432 | Two groups of six rhesus macaques (Macaca mulatta) received intradermal immunizations of plasmid DNA coding for SIV Eng and Gag, and influenza virus nucleoprotein (Flu-NP), with or without the co-administration of plasmid DNA coding for these cytokines. |
| 4 | 15214049 | The anti-tumor activity and production of autoantibodies against mouse endoglin could be abrogated by depletion of CD4(+) T lymphocytes. |
| 5 | 15687710 | These vaccines are delivered by attenuated Salmonella typhimurium to secondary lymphoid organs and are directed against novel targets such as transcription factor Fos-related antigen 1 (Fra-1) and endoglin (CD105). |
| 6 | 16565828 | We demonstrate that an endoglin vaccine elicited activation of antigen-presenting dendritic cells, coupled with immune responses mediated by CD8+ T cells against endoglin-positive target cells. |
| 7 | 17691024 | In addition, combination of endoglin DNA and recombinant protein vaccination significantly induced IFN-gamma secreting cells. |
| 8 | 21482223 | Vascular endothelial growth factor (VEGF) has been known as a potential vasculogenic and angiogenic factor and its receptor (VEGFR2) is a major receptor to response to the angiogenic activity of VEGF. |
| 9 | 21482223 | The inhibitive effects against angiogenesis were studied using CD31 and CD105 via histological analysis. |
| 10 | 21482223 | Antitumor activity and autoantibody production of mVEGFR2 could be neutralized by the depletion of CD4+T lymphocytes. |
| 11 | 25092771 | Tumor vasculature was measured by immunohistochemistry using three endothelial cell markers: CD31 (mature), CD105 (immature/proliferating), and CD11b (monocytic). |
| 12 | 25092771 | This combination therapy also increased TILs, including tumor antigen-specific CD8 T cells, and elevated the expression of activation markers FAS-L, CXCL-9, CD31, and CD105 in MDSCs and TAMs, leading to reduced tumor volumes and an increase in the number of tumor-free animals. |
| 13 | 25092771 | Tumor vasculature was measured by immunohistochemistry using three endothelial cell markers: CD31 (mature), CD105 (immature/proliferating), and CD11b (monocytic). |
| 14 | 25092771 | This combination therapy also increased TILs, including tumor antigen-specific CD8 T cells, and elevated the expression of activation markers FAS-L, CXCL-9, CD31, and CD105 in MDSCs and TAMs, leading to reduced tumor volumes and an increase in the number of tumor-free animals. |