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Gene Information
Gene symbol: ERBB4
Gene name: v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
HGNC ID: 3432
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | EGFR | 1 hits |
| 2 | ERBB2 | 1 hits |
| 3 | ERBB3 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 18523278 | CTLs directed against HER2 specifically cross-react with HER3 and HER4. |
| 2 | 18523278 | The human epidermal growth factor receptor 2 (HER2) has been targeted as a breast cancer-associated Ag by T cell-based immunotherapeutical strategies such as cancer vaccines and adoptive T cell transfer. |
| 3 | 18523278 | In this study, we generated human cytotoxic T cell clones directed against the HER2(369-377) epitope known to be naturally presented with HLA-A*0201. |
| 4 | 18523278 | Several HER2-expressing tumor cells became susceptible to CTL-mediated lysis after IFN-gamma treatment and, in parallel, up-regulated molecules of the Ag-presenting machinery, indicating that the tumor itself also contributes to the success of CTL-mediated killing. |
| 5 | 21603064 | The ErbB family (EGFR/ErbB1, ErbB2/HER2/neu, ErbB3/HER3 and ErbB4/HER4) of receptor tyrosine kinases (RTKs) have long been implicated in PCa initiation and progression, but inhibitors of ErbB1 and ErbB2 (prototypic family members) fared poorly in PCa clinical trials. |