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Gene Information
Gene symbol: ESAT
Gene name:
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CFP | 1 hits |
| 2 | IFNG | 1 hits |
| 3 | IL7 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15137119 | The results of deciphering the genome of M. tuberculosis and those of conducted studies have allowed the authors to substantiate the prospects of gene therapy of tuberculosis and its diagnosis by using the proteins CFP and ESAT, as well as new approaches to vaccine prevention. |
| 2 | 20231853 | Mice that received immunization with DNA constructs encoding M. bovis antigen 85A (Ag85-A) and arget(ESAT-6) produced measurable interferon-gamma (IFN-gamma) responses to CD4(+) T-cell epitope-peptide recall antigens in vitro. |
| 3 | 20231853 | The magnitude of these responses was enhanced by co-delivery of a construct encoding murine cytokines (macrophage inhibitory protein (MIP)-1 alpha or interleukin(IL)-7), although they did not the match responses observed in mice that received Bacille Calmette-Guerin(BCG) immunisation. |
| 4 | 20231853 | In contrast, DNA priming followed by boosting with modified vaccinia Ankara (MVA) vaccine (expressing M. tuberculosis Ag85-A) invoked higher IFN-gamma levels, with the most immunogenic regime of Ag85 or ESAT or IL-7 prime followed by MVA boost being of commensurate immunogenicity to BCG. |