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Gene Information

Gene symbol: EXOSC1

Gene name: exosome component 1

HGNC ID: 17286

Synonyms: hCsl4p, Csl4p, CSL4, Ski4p, SKI4, CGI-108, p13

Related Genes

# Gene Symbol Number of hits
1 APLP2 1 hits
2 CD4 1 hits
3 CDKN2A 1 hits
4 CREBBP 1 hits
5 EP300 1 hits
6 IFNG 1 hits
7 POLD4 1 hits
8 PRR6 1 hits

Related Sentences

# PMID Sentence
1 7972096 In addition to these activators, the bovine leukemia virus (BLV) and the human T-cell leukemia virus (HTLV) contain alternative open reading frames (R3 and G4 for BLV; p30, p13, and p12 for HTLV).
2 12654813 Testing of antigen-specific CD4(+) T-cell lines with the individual peptides of MPB70 confirmed that peptides p8, p12, and p13 contain immunodominant Th1 cell epitopes of MPB70.
3 12654813 The T-cell lines responding to MPB70 and peptides p8, p12, and p13 in IFN-gamma assays mediated antigen-peptide-specific cytotoxic activity against monocytes/macrophages pulsed with the whole-protein antigen or the peptides.
4 12654813 Testing of antigen-specific CD4(+) T-cell lines with the individual peptides of MPB70 confirmed that peptides p8, p12, and p13 contain immunodominant Th1 cell epitopes of MPB70.
5 12654813 The T-cell lines responding to MPB70 and peptides p8, p12, and p13 in IFN-gamma assays mediated antigen-peptide-specific cytotoxic activity against monocytes/macrophages pulsed with the whole-protein antigen or the peptides.
6 21677314 HTLV-1 replication is positively regulated by Tax and Rex and negatively regulated by the p30 and HBZ proteins.
7 21677314 The p13 protein directly binds Tax, decreases Tax binding to the CBP/p300 transcriptional coactivator, and, by reducing Tax transcriptional activity, suppresses viral expression.
8 21994758 Singly spliced mRNA from orf-I encodes p12, which can be proteolytically cleaved to generate p8, while differential splicing of mRNA from orf-II results in production of p13 and p30.
9 21994758 Though these proteins are not essential for virus replication in vitro, p8, p12, p13, and p30 have an important role in the establishment and maintenance of HTLV-1 infection in vivo.
10 21994758 Singly spliced mRNA from orf-I encodes p12, which can be proteolytically cleaved to generate p8, while differential splicing of mRNA from orf-II results in production of p13 and p30.
11 21994758 Though these proteins are not essential for virus replication in vitro, p8, p12, p13, and p30 have an important role in the establishment and maintenance of HTLV-1 infection in vivo.
12 24254845 Both peptides, P13 and P16, could form amyloid fibril structures to potently enhance HIV-1 infectivity.