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Gene Information
Gene symbol: EXOSC1
Gene name: exosome component 1
HGNC ID: 17286
Synonyms: hCsl4p, Csl4p, CSL4, Ski4p, SKI4, CGI-108, p13
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
7972096
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In addition to these activators, the bovine leukemia virus (BLV) and the human T-cell leukemia virus (HTLV) contain alternative open reading frames (R3 and G4 for BLV; p30, p13, and p12 for HTLV).
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2 |
12654813
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Testing of antigen-specific CD4(+) T-cell lines with the individual peptides of MPB70 confirmed that peptides p8, p12, and p13 contain immunodominant Th1 cell epitopes of MPB70.
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3 |
12654813
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The T-cell lines responding to MPB70 and peptides p8, p12, and p13 in IFN-gamma assays mediated antigen-peptide-specific cytotoxic activity against monocytes/macrophages pulsed with the whole-protein antigen or the peptides.
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4 |
12654813
|
Testing of antigen-specific CD4(+) T-cell lines with the individual peptides of MPB70 confirmed that peptides p8, p12, and p13 contain immunodominant Th1 cell epitopes of MPB70.
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5 |
12654813
|
The T-cell lines responding to MPB70 and peptides p8, p12, and p13 in IFN-gamma assays mediated antigen-peptide-specific cytotoxic activity against monocytes/macrophages pulsed with the whole-protein antigen or the peptides.
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6 |
21677314
|
HTLV-1 replication is positively regulated by Tax and Rex and negatively regulated by the p30 and HBZ proteins.
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7 |
21677314
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The p13 protein directly binds Tax, decreases Tax binding to the CBP/p300 transcriptional coactivator, and, by reducing Tax transcriptional activity, suppresses viral expression.
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8 |
21994758
|
Singly spliced mRNA from orf-I encodes p12, which can be proteolytically cleaved to generate p8, while differential splicing of mRNA from orf-II results in production of p13 and p30.
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9 |
21994758
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Though these proteins are not essential for virus replication in vitro, p8, p12, p13, and p30 have an important role in the establishment and maintenance of HTLV-1 infection in vivo.
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10 |
21994758
|
Singly spliced mRNA from orf-I encodes p12, which can be proteolytically cleaved to generate p8, while differential splicing of mRNA from orf-II results in production of p13 and p30.
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11 |
21994758
|
Though these proteins are not essential for virus replication in vitro, p8, p12, p13, and p30 have an important role in the establishment and maintenance of HTLV-1 infection in vivo.
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12 |
24254845
|
Both peptides, P13 and P16, could form amyloid fibril structures to potently enhance HIV-1 infectivity.
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