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Gene Information
Gene symbol: FANCC
Gene name: Fanconi anemia, complementation group C
HGNC ID: 3584
Synonyms: FAC, FA3
Related Genes
Related Sentences
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PMID |
Sentence |
1 |
10918477
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Ad infection (MOI 200) of BMDC induced significant increases in IL 12 p40 protein in culture supernatants (6 x that of uninfected BMDC and similar to that observed with addition of LPS and CD40 crosslinking antibody).
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2 |
10918477
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Consistent with DC activation, FACs analysis showed BMDC infected with Ad vectors up-regulated the surface expression of B7-2, ICAM-1 and MHC II.
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3 |
10918477
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Additional experiments evaluated the role of virus attachment, internalization and gene expression using IL-12 p40 production as a marker of DC activation.
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4 |
10918477
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Neither heat-inactivated Ad nor peptides containing the RGD sequence (the primary component of Ad penton base which interacts with cell surface integrins) induced significant amounts of IL12 p40.
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5 |
10918477
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In contrast, psoralen/UV-inactivated Ad showed similar levels of IL12 p40 production compared with intact Ad.
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