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Gene Information

Gene symbol: FANCC

Gene name: Fanconi anemia, complementation group C

HGNC ID: 3584

Synonyms: FAC, FA3

Related Genes

# Gene Symbol Number of hits
1 CD86 1 hits
2 HLA-A 1 hits
3 ICAM1 1 hits

Related Sentences

# PMID Sentence
1 10918477 Ad infection (MOI 200) of BMDC induced significant increases in IL 12 p40 protein in culture supernatants (6 x that of uninfected BMDC and similar to that observed with addition of LPS and CD40 crosslinking antibody).
2 10918477 Consistent with DC activation, FACs analysis showed BMDC infected with Ad vectors up-regulated the surface expression of B7-2, ICAM-1 and MHC II.
3 10918477 Additional experiments evaluated the role of virus attachment, internalization and gene expression using IL-12 p40 production as a marker of DC activation.
4 10918477 Neither heat-inactivated Ad nor peptides containing the RGD sequence (the primary component of Ad penton base which interacts with cell surface integrins) induced significant amounts of IL12 p40.
5 10918477 In contrast, psoralen/UV-inactivated Ad showed similar levels of IL12 p40 production compared with intact Ad.