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Gene Information

Gene symbol: FCAR

Gene name: Fc fragment of IgA, receptor for

HGNC ID: 3608

Synonyms: CD89

Related Genes

# Gene Symbol Number of hits
1 CD79A 1 hits
2 CR1 1 hits
3 ITGAM 1 hits
4 TDGF3 1 hits

Related Sentences

# PMID Sentence
1 10525053 Both S. pneumoniae-bound IgA and complement were involved, as demonstrated by a 50% decrease in killing with blocking of Fcalpha receptor (CD89) and CR1/CR3 (CD35/CD11b).
2 10525053 However, IgA-mediated killing by phagocytes could be reproduced in the absence of opsonic complement by pre-activating phagocytes with the inflammatory products C5a and TNF-alpha.
3 11447159 Both IgA and CD89 BsAb facilitated FcalphaRI-mediated binding, phagocytosis, and bacterial killing by human polymorphonuclear leukocytes (PMNL) and PMNL originating from human FcalphaRI-transgenic mice.