Ignet

Gene Information

Gene symbol: FCGR2B

Gene name: Fc fragment of IgG, low affinity IIb, receptor (CD32)

HGNC ID: 3618

Synonyms: CD32, CD32B

Related Genes

#	Gene Symbol	Number of hits
1	FCAMR	1 hits
2	FCGR1A	1 hits
3	FCGR2A	1 hits
4	FCGR2C	1 hits
5	FCGR3A	1 hits
6	FCGR3B	1 hits
7	FN1	1 hits

Related Sentences

#	PMID	Sentence
1	7930727	Fc gamma receptor IIa (CD32) heterogeneity in patients with recurrent bacterial respiratory tract infections.
2	7930727	Fc gamma RIIa (CD32) is the sole IgG Fc receptor capable of interaction with human IgG2, the main IgG subclass of bacterial capsular polysaccharides.
3	7930727	The capacity of polymorphonuclear leukocytes (PMNL) homozygous for Fc gamma RIIa-H/H131 for IgG2 opsonized bacteria is significantly higher than phagocytosis by PMNL homozygous for Fc gamma RIIa-R/R131, independent of the Fc gamma RIIb-NA1/NA2 (CD16) allelic polymorphism.
4	7930727	Fc gamma receptor IIa (CD32) heterogeneity in patients with recurrent bacterial respiratory tract infections.
5	7930727	Fc gamma RIIa (CD32) is the sole IgG Fc receptor capable of interaction with human IgG2, the main IgG subclass of bacterial capsular polysaccharides.
6	7930727	The capacity of polymorphonuclear leukocytes (PMNL) homozygous for Fc gamma RIIa-H/H131 for IgG2 opsonized bacteria is significantly higher than phagocytosis by PMNL homozygous for Fc gamma RIIa-R/R131, independent of the Fc gamma RIIb-NA1/NA2 (CD16) allelic polymorphism.
7	7930727	Fc gamma receptor IIa (CD32) heterogeneity in patients with recurrent bacterial respiratory tract infections.
8	7930727	Fc gamma RIIa (CD32) is the sole IgG Fc receptor capable of interaction with human IgG2, the main IgG subclass of bacterial capsular polysaccharides.
9	7930727	The capacity of polymorphonuclear leukocytes (PMNL) homozygous for Fc gamma RIIa-H/H131 for IgG2 opsonized bacteria is significantly higher than phagocytosis by PMNL homozygous for Fc gamma RIIa-R/R131, independent of the Fc gamma RIIb-NA1/NA2 (CD16) allelic polymorphism.
10	16412049	Novel roles of osteopontin and CXC chemokine ligand 7 in the defence against mycobacterial infection.
11	16412049	Granulocyte-macrophage colony-stimulating factor (GM-CSF)-induced human monocyte-derived macrophage (GM-Mphi) or macrophage CSF (M-CSF)-induced human monocyte-derived Mphi (M-Mphi) are distinct in terms of the resistance to Mycobacterium tuberculosis.
12	16412049	FN1 and FCGR2B were the most up-regulated genes in GM-Mphi and M-Mphi, respectively.
13	16412049	After stimulation with BCG, three chemokine genes (Osteopontin (SPP1), CXC chemokine ligand 7 (CXCL7) and CC chemokine ligand 11 (CCL11)) were highly expressed in M-Mphi-BCG when compared to those in GM-Mphi-BCG.
14	16412049	A significantly increased resistance to M. tuberculosis H37Ra was observed after the stimulation of GM-Mphi with SPP1 or CXCL7.
15	16412049	Superoxide production levels of SPP1- or CXCL7-stimulated GM-Mphis were higher than those of GM-Mphis without stimulation.
16	16412049	These results indicate that both SPP1 and CXCL7 might have a role in the resistance against mycobacteria, at least in part, through augmenting reactive oxygen intermediate production in Mphis.
17	22760702	The inhibitory Fc gamma receptor II (FcγRIIB; CD32) is central to this regulation with FcγRIIB(-/-) mice demonstrating augmented responses to mAb immunotherapy, elevated incidence and severity of auto-immunity, and increased response to mAb-mediated cancer therapy.
18	24989892	Polymorphisms within FCGR2A and FCGR3A are associated with binding affinity of natural killer cells to the IgG1 portion of trastuzumab, and a polymorphism in FCGR2B (I232T) is associated with impaired regulatory activity.
19	24989892	We performed genotyping analysis on the FCGR3A V158F, FCGR2A R131H, and FCGR2B I232T polymorphisms in 1,325 patients from the N9831 clinical trial.
20	24989892	We found no differences in DFS between trastuzumab-treated patients who had the FCGR3A 158 V/V and/or FCGR2A 131 H/H high-affinity genotypes and patients without those genotypes.
21	24989892	Furthermore, there was no significant interaction between FCGR3A and FCGR2A and treatment.
22	24989892	Polymorphisms within FCGR2A and FCGR3A are associated with binding affinity of natural killer cells to the IgG1 portion of trastuzumab, and a polymorphism in FCGR2B (I232T) is associated with impaired regulatory activity.
23	24989892	We performed genotyping analysis on the FCGR3A V158F, FCGR2A R131H, and FCGR2B I232T polymorphisms in 1,325 patients from the N9831 clinical trial.
24	24989892	We found no differences in DFS between trastuzumab-treated patients who had the FCGR3A 158 V/V and/or FCGR2A 131 H/H high-affinity genotypes and patients without those genotypes.
25	24989892	Furthermore, there was no significant interaction between FCGR3A and FCGR2A and treatment.
26	25142001	Expression of the inhibitory Fc gamma receptor IIB (FCGR2B, CD32B) on follicular lymphoma cells lowers the response rate to rituximab monotherapy (SAKK 35/98).