Ignet

Gene Information

Gene symbol: FCN2

Gene name: ficolin (collagen/fibrinogen domain containing lectin) 2 (hucolin)

HGNC ID: 3624

Synonyms: P35, FCNL, EBP-37, ficolin-2

Related Genes

#	Gene Symbol	Number of hits
1	FCN1	1 hits
2	FCN3	1 hits
3	MBL2	1 hits

Related Sentences

#	PMID	Sentence
1	24173025	Blood collection tubes influence serum ficolin-1 and ficolin-2 levels.
2	24173025	Ficolin-1 (M-ficolin) and ficolin-2 (L-ficolin) are known to bind Streptococcus pneumoniae serotypes 19C and 11A, respectively.
3	24173025	We found that the silica clot activator eluted from plastic red-top tubes inhibited ficolin-2 ligand binding, while other related proteins, like mannose-binding lectin (MBL) and ficolin-1, were not affected.
4	24173025	These tube types did not affect the concentrations of other related opsonins (C1q, MBL, or ficolin-3 [H-ficolin]).
5	24173025	These findings have implications for future ficolin-1 and ficolin-2 studies, as proper sample collection and handling are essential.
6	24173025	Blood collection tubes influence serum ficolin-1 and ficolin-2 levels.
7	24173025	Ficolin-1 (M-ficolin) and ficolin-2 (L-ficolin) are known to bind Streptococcus pneumoniae serotypes 19C and 11A, respectively.
8	24173025	We found that the silica clot activator eluted from plastic red-top tubes inhibited ficolin-2 ligand binding, while other related proteins, like mannose-binding lectin (MBL) and ficolin-1, were not affected.
9	24173025	These tube types did not affect the concentrations of other related opsonins (C1q, MBL, or ficolin-3 [H-ficolin]).
10	24173025	These findings have implications for future ficolin-1 and ficolin-2 studies, as proper sample collection and handling are essential.
11	24173025	Blood collection tubes influence serum ficolin-1 and ficolin-2 levels.
12	24173025	Ficolin-1 (M-ficolin) and ficolin-2 (L-ficolin) are known to bind Streptococcus pneumoniae serotypes 19C and 11A, respectively.
13	24173025	We found that the silica clot activator eluted from plastic red-top tubes inhibited ficolin-2 ligand binding, while other related proteins, like mannose-binding lectin (MBL) and ficolin-1, were not affected.
14	24173025	These tube types did not affect the concentrations of other related opsonins (C1q, MBL, or ficolin-3 [H-ficolin]).
15	24173025	These findings have implications for future ficolin-1 and ficolin-2 studies, as proper sample collection and handling are essential.
16	24173025	Blood collection tubes influence serum ficolin-1 and ficolin-2 levels.
17	24173025	Ficolin-1 (M-ficolin) and ficolin-2 (L-ficolin) are known to bind Streptococcus pneumoniae serotypes 19C and 11A, respectively.
18	24173025	We found that the silica clot activator eluted from plastic red-top tubes inhibited ficolin-2 ligand binding, while other related proteins, like mannose-binding lectin (MBL) and ficolin-1, were not affected.
19	24173025	These tube types did not affect the concentrations of other related opsonins (C1q, MBL, or ficolin-3 [H-ficolin]).
20	24173025	These findings have implications for future ficolin-1 and ficolin-2 studies, as proper sample collection and handling are essential.
21	25030054	The ficolins are a family of innate pattern recognition molecules that are known to bind acetylated compounds and activate complement through the association of mannose binding lectin (MBL)/ficolin-associated serine proteases (MASPs).
22	25030054	While studying ficolin-2-mediated complement deposition on Streptococcus pneumoniae, we found that sera depleted of C1q or other complement components were also codepleted of ficolin-2 but not ficolin-1, ficolin-3, or MBL.
23	25030054	MBL present in C1q-depleted sera was able to mediate complement deposition on Saccharomyces cerevisiae, suggesting the presence of MASPs.