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Gene Information
Gene symbol: FKBP1A
Gene name: FK506 binding protein 1A, 12kDa
HGNC ID: 3711
Synonyms: FKBP-12, FKBP12, PKC12, PPIASE, FKBP12C
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | CD40 | 1 hits |
| 2 | CD8A | 1 hits |
| 3 | FARSA | 1 hits |
| 4 | FKBP11 | 1 hits |
| 5 | FKBP1B | 1 hits |
| 6 | GAPDH | 1 hits |
| 7 | MYD88 | 1 hits |
| 8 | NEU1 | 1 hits |
| 9 | PPIA | 1 hits |
| 10 | PPIB | 1 hits |
| 11 | PPIC | 1 hits |
| 12 | PPIH | 1 hits |
| 13 | SH2D3A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 19543266 | Experiments using RNA interference to inhibit expression of mTOR, raptor (also known as 4932417H02Rik) or FKBP12 (also known as FKBP1A) in antigen-specific CD8 T cells showed that mTOR acts intrinsically through the mTORC1 (mTOR complex 1) pathway to regulate memory T-cell differentiation. |
| 2 | 21383499 | A composite MyD88/CD40 switch synergistically activates mouse and human dendritic cells for enhanced antitumor efficacy. |
| 3 | 21383499 | Here, we have engineered a drug-inducible, composite activation receptor for DCs (referred to herein as DC-CAR) comprising the TLR adaptor MyD88, the CD40 cytoplasmic region, and 2 ligand-binding FKBP12 domains. |
| 4 | 21383499 | AP1903-activated iMyD88/CD40-transduced human or mouse DCs also produced higher levels of Th1 cytokines, showed improved migration in vivo, and enhanced both antigen-specific CD8+ T cell responses and innate NK cell responses. |
| 5 | 22046132 | In this study, we used a systems biology approach employing a genome-wide yeast-two hybrid interaction screen to identify immunopilins (PPIA, PPIB, PPIH, PPIG, FKBP1A, FKBP1B) as interaction partners of the CoV non-structural protein 1 (Nsp1). |
| 6 | 22046132 | Overexpression of NSP1 and infection with live SARS-CoV strongly increased signalling through the Calcineurin/NFAT pathway and enhanced the induction of interleukin 2, compatible with late-stage immunopathogenicity and long-term cytokine dysregulation as observed in severe SARS cases. |
| 7 | 22125074 | Here, we provide a detailed protocol for knocking down mTOR and its related molecules (raptor and FKBP12) in antigen-specific CD8 T cells. |
| 8 | 22806993 | Solution structure of FK506-binding protein 12 from Aedes aegypti. |
| 9 | 23266097 | Among them, six proteins (FKBP-type peptidyl-prolyl cis-trans isomerase, neuraminidase exo-α-sialidase, xanthine-guanine phosphoribosyl transferase, CMP-N-acetylneuraminic acid synthetase, phenylalanyl-tRNA synthetase and glyceraldehyde 3-phosphate dehydrogenase) were found to be novel immunogens in H. parasuis. |
| 10 | 25369230 | Comparison between the three extraction methods by Venn diagram and subcellular localization predictors (CELLO v.2.5 and Gpos-mPLoc) allowed us to identify six proteins that are most likely surface-exposed: the SCP-like extracellular protein, a low affinity penicillin-binding protein 5 (PBP5), a basic membrane lipoprotein, a peptidoglycan-binding protein LysM (LysM), a D-alanyl-D-alanine carboxypeptidase (DdcP) and the peptidyl-prolyl cis-trans isomerase (PpiC). |