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Gene Information
Gene symbol: FLNB
Gene name: filamin B, beta
HGNC ID: 3755
Synonyms: TAP, TABP, ABP-278, FH1
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | B2M | 1 hits |
| 2 | ERAP1 | 1 hits |
| 3 | FCAMR | 1 hits |
| 4 | HLA-A | 1 hits |
| 5 | HLA-DMA | 1 hits |
| 6 | HSPA1A | 1 hits |
| 7 | IFNG | 1 hits |
| 8 | NRSN1 | 1 hits |
| 9 | POLE3 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 10319257 | The BoLA region is unlike the MHC of humans and mice in that a large inversion has moved several class II genes, including the TAP/LMP cluster, close to the centromere of bovine chromosome 23. |
| 2 | 12093890 | Here we show that targeting of antigen to Fc receptors on DCs accomplishes combined activation of Th1 CD4 and CD8 effector responses in vivo, namely delayed-type hypersensitivity and tumor immunity. |
| 3 | 12093890 | Tumor protection was eliminated when immune complex-loaded DCs lacked beta(2) microglobulin, TAP, or MHC class II, demonstrating that Fc receptor-targeted antigenic uptake led to both MHC class I- and class II-restricted responses, which together are required for effector tumor immunity. |
| 4 | 12918137 | Expression of class I MHC molecule, HSP70 and TAP in human hepatocellular carcinoma. |
| 5 | 15034075 | Our previous work demonstrated that Trojan Ags containing a CTL epitope localized to intracellular compartments, where MHC class I-binding peptides were generated in a TAP-independent fashion by the action of various exopeptidases and the endopeptidase furin. |
| 6 | 15165177 | HLA class I and class II, TAP, and HLA-DM allele associations with measles-specific antibody levels following measles vaccination have revealed, in part, the immunologic basis for mechanisms of measles immunity variation. |
| 7 | 16930710 | For a given virus, we use algorithms computing: peptide cleavage probability, transfer through TAP and MHC binding for a large number of HLA alleles. |
| 8 | 19412183 | We show here that CTL immunodominance in regions of the human immunodeficiency virus type 1 group-associated antigen proteins p17 and p24 correlated with epitope abundance, which was strongly influenced by proteasomal digestion profiles, affinity for the transporter protein TAP, and trimming mediated by the endoplasmatic reticulum aminopeptidase ERAAP, and was moderately influenced by HLA affinity. |
| 9 | 23056548 | To maximize antigen presentation in target cells, both MHC class I and TAP protein expression was induced in RM-1 cells by transduction with an Ad vector expressing interferon-gamma (Ad5-IFNγ). |
| 10 | 23056548 | Administering DCs infected ex vivo with CD40-targeted Ad5-huPSMA, as well as direct intraperitoneal injection of the vector, resulted in high levels of tumor-specific CTL responses against RM-1-PSMA cells pretreated with Ad5-IFNγ as target cells. |