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Gene Information
Gene symbol: FLOT1
Gene name: flotillin 1
HGNC ID: 3757
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | TFRC | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 24422228 | We tested whether a Virulence Associated Protein A (VapA)/CpG vaccine against R. equi would impact the production of IL-10, IFN-γ and TNF-α in lung tissue and fluid samples, alter expression of TLR2 and TLR4 and alter their association with the lipid rafts in broncho-alveolar lavage (BAL) cells. |
| 2 | 24422228 | We report adaptation of previous protocols to isolate plasma membrane fractions from BAL cells and identification of lipid raft fractions based on the presence of flotillin-1 and GM-1 and absence of transferrin receptor. |
| 3 | 24422228 | TLR2 and TLR4 were restricted to plasma membrane fractions 7–9 of alveolar cells collected from vaccinated foals before and after the challenge. |
| 4 | 24422228 | Taken together, we modified previous protocols to isolate plasma membrane fractions from BAL cells of foals and report that the vaccination with a VapA/CPG vaccine increases association of TLR2 and TLR4 with lipid raft fractions and alters expression of TNF-α and IL-10. |
| 5 | 24422228 | The data point to a subtle effect of vaccination on the association of TLR2 and TLR4 with lipid rafts in BAL cells. |