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Gene Information
Gene symbol: FOXP2
Gene name: forkhead box P2
HGNC ID: 13875
Synonyms: CAGH44
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | FOXP3 | 1 hits |
| 2 | GABRE | 1 hits |
| 3 | IMMP2L | 1 hits |
| 4 | RELN | 1 hits |
| 5 | ST7 | 1 hits |
| 6 | TNFRSF1A | 1 hits |
| 7 | UBE3A | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 15121991 | Among other candidate genes are the FOXP2, RAY1/ST7, IMMP2L, and RELN genes at 7q22-q33 and the GABA(A) receptor subunit and UBE3A genes on chromosome 15q11-q13. |
| 2 | 20870946 | Using a phage-displayed random peptide library, we identified a 15-mer synthetic peptide, P60, able to bind to forkhead/winged helix transcription factor 3 (FOXP3), a factor required for development and function of Treg. |
| 3 | 20870946 | P60 enters the cells, inhibits FOXP3 nuclear translocation, and reduces its ability to suppress the transcription factors NF-κB and NFAT. |
| 4 | 20870946 | P60 administration to newborn mice induced a lymphoproliferative autoimmune syndrome resembling the reported pathology in scurfy mice lacking functional Foxp3. |
| 5 | 20870946 | Similarly, P60 improved the antiviral efficacy of a recombinant adenovirus expressing NS3 protein from hepatitis C virus. |
| 6 | 20870946 | Functional inhibition of Treg by the FOXP3-inhibitory peptide P60 constitutes a strategy to enhance antitumor and antiviral immunotherapies. |