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Gene Information
Gene symbol: GBGT1
Gene name: globoside alpha-1,3-N-acetylgalactosaminyltransferase 1
HGNC ID: 20460
Synonyms: UDP-GalNAc, A3GALNT, MGC44848, FS
Related Genes
| # | Gene Symbol | Number of hits |
| 1 | GNB5 | 1 hits |
| 2 | POMGNT1 | 1 hits |
Related Sentences
| # | PMID | Sentence |
| 1 | 16800641 | These results show that the biosynthesis of Vi antigen is initiated by the TviB-catalyzed oxidation of UDP-GlcNAc to UDP-GalNAc, followed by the TviC-catalyzed epimerization at C-4 to form UDP-GalNAcA, which serves as the building block for the formation of Vi polymer. |
| 2 | 24044869 | We report here the development of chemoenzymatic methods for the large-scale synthesis of cancer-associated antigens globopentaose (Gb5), fucosyl-Gb5 (Globo H), and sialyl-Gb5 (SSEA4) by using overexpressed glycosyltransferases coupled with effective regeneration of sugar nucleotides, including UDP-Gal, UDP-GalNAc, GDP-Fuc, and CMP-Neu5Ac. |