Ignet

Gene Information

Gene symbol: GFAP

Gene name: glial fibrillary acidic protein

HGNC ID: 4235

Synonyms: FLJ45472

Related Genes

#	Gene Symbol	Number of hits
1	ACTC1	1 hits
2	APP	1 hits
3	BAX	1 hits
4	CANX	1 hits
5	CHL1	1 hits
6	CLU	1 hits
7	COL1A1	1 hits
8	DES	1 hits
9	HSPD1	1 hits
10	IDH1	1 hits
11	IL10	1 hits
12	IL1B	1 hits
13	MBP	1 hits
14	MLANA	1 hits
15	NGFR	1 hits
16	NME2	1 hits
17	OLIG2	1 hits
18	PRNP	1 hits
19	RANBP2	1 hits
20	SRC	1 hits
21	TEGT	1 hits
22	TNF	1 hits
23	TP53	1 hits
24	VIM	1 hits

Related Sentences

#	PMID	Sentence
1	3021915	This cell line provides a GFAP-expressing brain tumor model that extends the use of autochthonous ASV-induced astrocytomas by allowing in vitro and in vivo studies.
2	7483906	Porencephalic cysts were surrounded by astrocytes with increased expression of GFAP and vimentin-positive cells and cell processes.
3	11857388	Autologous and allogeneic SEREX analysis of >5 x 10(6) clones with the sera of 18 astrocytoma patients revealed 10 antigens: the differentiation antigen glial fibrillary acidic protein (GFAP), Bax-inhibitor 1 (which was overexpressed in all glioma samples tested), 3 other molecules involved in the regulation of gene expression and proliferation (the nm23-H2-encoded nucleoside diphosphate kinase B, the Ran binding protein-2 and a DNA binding protein encoded by the son gene), SP40,40 (a complement inhibitory molecule), the chaperonin TCP-1, calnexin and 2 new gene products.
4	11857388	Antibody responses in astrocytoma patients against antigens expressed by gliomas were rare and, with the exception of Bax-inhibitor 1 and the product of the son gene, were also found in apparently healthy controls.
5	12824506	In addition, tumors were examined for expression of vimentin, cytokeratin, smooth muscle actin, desmin, melan A, neural cell adhesion molecule, S-100, glial fibrillary acidic protein, nerve growth factor receptor, and collagen type IV.
6	12824506	On the basis of collagen type IV and crystallin alpha A immunopositivity, we established that three of nine tumors were of lens epithelial origin.
7	12824506	Expression of desmin and smooth muscle actin identified one tumor as a leiomyosarcoma.
8	15780734	For each hamster included in the study, prion-specific serum antibodies as well as deposition of pathological prion protein (PrP(res)), glial fibrillary acidic protein (GFAP), and mRNA expression for cytokines (TNF alpha, IL-1beta, IL-10) in brain tissues were evaluated.
9	15780734	In immunized animals, increased survival after challenge was associated with a reduction of cerebral lesion, PrP deposition and GFAP expression; in these animals, anti-prion protein peptide antibody levels were increased, and the expression of pro-inflammatory cytokines (TNF alpha and IL-1beta) was reduced.
10	15780734	For each hamster included in the study, prion-specific serum antibodies as well as deposition of pathological prion protein (PrP(res)), glial fibrillary acidic protein (GFAP), and mRNA expression for cytokines (TNF alpha, IL-1beta, IL-10) in brain tissues were evaluated.
11	15780734	In immunized animals, increased survival after challenge was associated with a reduction of cerebral lesion, PrP deposition and GFAP expression; in these animals, anti-prion protein peptide antibody levels were increased, and the expression of pro-inflammatory cytokines (TNF alpha and IL-1beta) was reduced.
12	16972888	Resolution process of cerebroparenchymal amyloid beta-protein (Abeta) deposition has become of increasing interest in the light of recent advance in the Abeta-vaccination therapy for Alzheimer's disease (AD).
13	16972888	To clarify the natural removal processes of Abeta burden in the brain with AD, we devised a triple-step staining method: Bodian for dystrophic neurites, anti-glial fibrillary acidic protein for astrocytes, and anti-Abeta.
14	24765187	The current study presents a highly aggressive case of small cell GB as diagnosed by histological features and immunohistochemistry for vimentin, glial fibrillary acidic protein, oligodendrocyte lineage transcription factor 2, isocitrate dehydrogenase 1-R132H and p53.
15	25124724	Concentrations of IgM and IgG autoantibodies specific to both neural (neurofilaments, cholineacetyltransferase, astrocyte glial fibrillary acidic protein, and myelin basic protein) and non-neural (actin, desmin, and keratin) antigens were measured and the associations of these autoantibody concentrations with chemical exposures were assessed using linear regression.